Regiospecific Synthesis of 4-Alkoxy and 4-Amino Substituted 2-Trifluoromethyl Pyrroles
| Autor: | Paulo H. Schneider, Marcos A. P. Martins, Ana D. Wouters, Nilo Zanatta, Ludger A. Wessjohann, Juliana M. F. M. Schneider, Helio G. Bonacorso |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Magnetic Resonance Spectroscopy
Trifluoromethyl Hydrocarbons Fluorinated Molecular Structure Chemistry Organic Chemistry Chemistry Organic Stereoisomerism General Medicine Chemical synthesis Pyrrole derivatives chemistry.chemical_compound Alkoxy group Molecule Organic chemistry Pyrroles Amine gas treating Azide |
| Zdroj: | The Journal of Organic Chemistry. 71:6996-6998 |
| ISSN: | 1520-6904 0022-3263 |
| Popis: | A simple and regiospecific synthesis of 4-alkoxy(amino)-2-trifluoromethyl pyrroles from 5-azido-4-alkoxy(amino)-1,1,1-trifluoro-pent-3-en-2-ones by an aza-Wittig cyclization of aminophosphoranes is described. The structures of the pyrroles and their synthetic intermediates were supported by NMR and HRMS analysis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|