Pedunculopontine Gamma Band Activity and Development

Autor: Melanie C. MacNicol, Brennon Luster, Edgar Garcia-Rill, James Hyde, Stasia D'Onofrio, Susan Mahaffey, Cristy Phillips
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Brain Sciences, Vol 5, Iss 4, Pp 546-567 (2015)
Brain Sciences
ISSN: 2076-3425
Popis: This review highlights the most important discovery in the reticular activating system in the last 10 years, the manifestation of gamma band activity in cells of the reticular activating system (RAS), especially in the pedunculopontine nucleus, which is in charge of waking and rapid eye movement (REM) sleep. The identification of different cell groups manifesting P/Q-type Ca(2+) channels that control waking vs. those that manifest N-type channels that control REM sleep provides novel avenues for the differential control of waking vs. REM sleep. Recent discoveries on the development of this system can help explain the developmental decrease in REM sleep and the basic rest-activity cycle.
Databáze: OpenAIRE