FSH: III. Evidence for a Possible Prepubertal Regulation of its Secretion by the Seminiferous Tubules in Cryptorchid Boys *
| Autor: | Anne-Marie Schindler, Pierre C. Sizonenko, Wolfgang Roland, Antoine Cuendet, Luc Paunier |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Male
medicine.medical_specialty Endocrinology Diabetes and Metabolism Clinical Biochemistry Gonadotropin-releasing hormone Biochemistry Gonadotropin-Releasing Hormone Endocrinology Internal medicine Cryptorchidism Testis Biopsy medicine Humans Secretion Child Normal range Dose-Response Relationship Drug medicine.diagnostic_test business.industry Puberty Biochemistry (medical) Luteinizing Hormone Seminiferous Tubules Child Preschool Stimulation tests Follicle Stimulating Hormone business |
| Zdroj: | The Journal of Clinical Endocrinology & Metabolism. 46:301-308 |
| ISSN: | 1945-7197 0021-972X |
| DOI: | 10.1210/jcem-46-2-301 |
| Popis: | Two groups of prepubertal unilateral cryptorchid boys, 42▵12 to 12 years of age, underwent stimulation tests with 1 μg (n = 10) or 25 μg (n = = 8) of LHRH. Two groups of prepubertal bilateral cryptorchid boys, 52▵12 to H9▵12 years of age, were similarly studied (1 μg, n = 6; 25 μg, n = 8). For comparison, control groups of both prepubertal boys, 66▵12 to 119▵12 Via years of age (1 μg, n = 9; 25 μg, n = 11), and pubertal boys, 12 5/12 to 14 years of age (1 μg, n = 11), were also tested for response to LHRH. All patients had surgical descents of the cryptorchid testes with bilateral biopsy of the testes at that time. The number of spermatogonia per 50 transverse tubular sections was determined. Unilateral cryptorchid groups exhibited FSH responses to 1 and 25 μg of LHRH similar to those of the prepubertal control groups. The numbers of spermatogonia were low (means ± SE of 12 ± 6 to 25 ± 12) on the cryptorchid side, and in the normal range (greater than 50 per 50 tubular transverse sections) on the normal s... |
| Databáze: | OpenAIRE |
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