Benign giant-cell tumor of the common bile duct: A case report
| Autor: | Lianghong Teng, Dandan Wang, Yan-Ni Sun, Wei Gao, Yue-Hua Wang, Yamin Zheng, De-Hong Lu, Leiming Wang, Fei Li |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Male
Pathology medicine.medical_specialty Cholangiopancreatography Magnetic Resonance medicine.medical_treatment Biopsy Common Bile Duct Neoplasms Jejunostomy Antigens Differentiation Myelomonocytic Case Report Receptors Cell Surface Antigens CD medicine Biomarkers Tumor Humans Cholecystectomy Giant Cell Tumors Aged 80 and over medicine.diagnostic_test Common bile duct Bile duct CD68 business.industry Gallbladder Gastroenterology Anastomosis Roux-en-Y General Medicine Immunohistochemistry Tumor Burden medicine.anatomical_structure Treatment Outcome Giant cell business Tomography X-Ray Computed |
| Popis: | Primary giant-cell tumors rarely arise in the common bile duct. We herein report a case of primary giant-cell tumor of the common bile duct. The patient was an 81-year-old male who was diagnosed with a well-defined 1.2-cm mass projecting into the lumen of the middle common bile duct. Excision of the gallbladder and extrahepatic bile duct and a Roux-en-Y cholangiojejunostomy were performed. Histologically, the tumor had no association with carcinomas of epithelial origin and was similar to giant-cell tumors of the bone. The tumor consisted of a mixture of mononuclear and multinucleated osteoclast-like giant cells. The mononuclear cells showed no atypical features, and their nuclei were similar to those of the multinucleated giant cells. CD68 was expressed on the mononuclear and multinucleated osteoclast-like giant cells, whereas CD163 immunoreactivity was restricted to the mononuclear cells. Six months after the operation, the patient was still alive and had no recurrence. The interest of this case lies in the rarity of this entity, the difficulty of preoperative diagnosis, and this tumor's possible confusion with other malignant tumors. |
| Databáze: | OpenAIRE |
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