Levamisole-adulterated cocaine: a case series
| Autor: | Dale A. Patterson, Rachael Harris Sprunger, Bryan C. Mason, Luke A. White, Holly Hake Harris, Gerald W. Morris |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Biopsy Cocaine-Related Disorders Young Adult medicine Humans Clinical syndrome Skin Leukopenia business.industry Public health Public Health Environmental and Occupational Health Levamisole Middle Aged Dermatology United States Leukocytoclastic vasculitis Skin grafting Female medicine.symptom Family Practice business Skin lesion Drug Contamination medicine.drug |
| Zdroj: | Journal of the American Board of Family Medicine : JABFM. 25(4) |
| ISSN: | 1558-7118 |
| Popis: | The percentage of cocaine adulterated with levamisole is steadily increasing in the United States. In susceptible persons, this combination of drugs leads to a clinical syndrome that can include leukopenia and cutaneous manifestations. Many patients also demonstrate positive autoimmune markers. Biopsies of skin lesions often reveal a thrombotic pattern, leukocytoclastic vasculitis, or both. We report 2 cases of this clinical phenomenon, one of which was severe enough to require skin grafting. It is important for clinicians be aware of this emerging public health threat. |
| Databáze: | OpenAIRE |
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