Effects of Comorbid Sleep Disorders on Cardiovascular Complications of Hypertension Among Patients With Newly-diagnosed Hypertension: An Analysis of the Korean National Health Insurance Service-National Sample Cohort

Autor: Young Hwangbo, Yoon-Hyung Park, Jose Rene Bagani Cruz, Kwang Ik Yang, Jeongmook Kang
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Adult
Male
medicine.medical_specialty
National Health Programs
Population
lcsh:Medicine
Comorbidity
Essential hypertension
01 natural sciences
Cohort Studies
03 medical and health sciences
0302 clinical medicine
Risk Factors
cardiovascular disease
Internal medicine
Diabetes mellitus
Republic of Korea
medicine
Humans
030212 general & internal medicine
cardiovascular diseases
0101 mathematics
education
Aged
Aged
80 and over
education.field_of_study
sleep wake disorders
business.industry
Incidence (epidemiology)
lcsh:Public aspects of medicine
010102 general mathematics
lcsh:R
Public Health
Environmental and Occupational Health
essential hypertension
lcsh:RA1-1270
Middle Aged
medicine.disease
Cardiovascular Diseases
Hypertension
Attributable risk
Cohort
incidence
Population study
Female
Original Article
Complications of hypertension
business
Zdroj: Journal of Preventive Medicine and Public Health, Vol 53, Iss 1, Pp 37-44 (2020)
Journal of Preventive Medicine and Public Health
ISSN: 2233-4521
1975-8375
Popis: Objectives This study investigated the effects of comorbid sleep disorders (SD) on the incidence of cardiovascular complications among newly-diagnosed hypertension (HTN) patients. Methods As study population, 124 057 newly-diagnosed essential HTN patients aged 30 or older, without cardiovascular complications at diagnosis with HTN, were selected from the National Health Insurance Service-National Sample Cohort. The incidence of cardiovascular complications was calculated, Cox proportional-hazards regression model was used to analyze the risk of complications, and the population attributable fraction (PAF) for cardiovascular complications of having comorbid SD at HTN diagnosis was calculated. Results Over 10 years, 32 275 patients (26.0%) developed cardiovascular complications. In HTN patients with comorbid SD at diagnosis of HTN, the incidence of cardiovascular complications (78.3/1000 person-years; 95% confidence interval [CI], 75.8 to 80.9) was higher than in those without comorbid SD (58.6/1000 person-years; 95% CI, 57.9 to 59.3) and the risk of cardiovascular complications was 1.21 times higher (95% CI, 1.17 to 1.25), adjusting for age, gender, income, area of residence, and comorbid diabetes mellitus. The PAF of having comorbid SD at diagnosis of HTN for the incidence of cardiovascular complications was 2.07% (95% CI, 1.69 to 2.44). Conclusions Newly-diagnosed essential HTN patients aged 30 or older who had comorbid SD at the time of their HTN diagnosis had a higher incidence of cardiovascular complications than those without comorbid SD. Age, gender, income, area of residence, and comorbid diabetes mellitus had a significant effect on the incidence of cardiovascular complications. Approximately 2% of cardiovascular complications were found to occur due to the presence of SD.
Databáze: OpenAIRE
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