Acupuncture for Poor Ovarian Response: A Randomized Controlled Trial
Autor: | Jihyun Kim, Byoung-Kab Kang, Kyu Sup Lee, Joong Il Kim, Myeong Soo Lee, Tae-Young Choi, Jong Kil Joo, Sooseong You, Hoyoung Lee |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
medicine.medical_treatment Controlled ovarian hyperstimulation Article law.invention 03 medical and health sciences oocyte retrieval 0302 clinical medicine Randomized controlled trial law poor ovarian response Acupuncture Medicine Ovarian reserve network analysis reproductive and urinary physiology Ivf treatment 030219 obstetrics & reproductive medicine In vitro fertilisation business.industry Obstetrics General Medicine University hospital female genital diseases and pregnancy complications 030220 oncology & carcinogenesis Negative correlation business in vitro fertilization acupuncture |
Zdroj: | Journal of Clinical Medicine Journal of Clinical Medicine, Vol 10, Iss 2182, p 2182 (2021) |
ISSN: | 2077-0383 |
Popis: | Acupuncture is believed to improve ovarian reserve and reproductive outcomes in women undergoing in vitro fertilization (IVF). This study was conducted to evaluate the effect of network-optimized acupuncture followed by IVF on the oocyte yield in women showing a poor ovarian response. This study was an exploratory randomized controlled trial conducted from June 2017 to January 2020 at the Pusan National University Hospital. Women diagnosed with poor ovarian response were enrolled and randomly divided into two groups: IVF alone and Ac + IVF groups (16 acupuncture sessions before IVF treatment). Eight acupoints with high degree centrality and betweenness centrality were selected using network analysis. Among the participants, compared with the IVF treatment alone, the acupuncture + IVF treatment significantly increased the number of retrieved mature oocytes in women aged more than 37 years and in those undergoing more than one controlled ovarian hyperstimulation cycle. The negative correlation between the number of retrieved mature oocytes and consecutive controlled ovarian hyperstimulation cycles was not observed in the Ac + IVF group irrespective of the maternal age. These findings suggest that physicians can consider acupuncture for the treatment of women with poor ovarian response and aged > 37 years or undergoing multiple IVF cycles. |
Databáze: | OpenAIRE |
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