Empagliflozin improves primary haemodynamic parameters and attenuates the development of atherosclerosis in high fat diet fed APOE knockout mice

Autor:	Georgios Agrogiannis, Eva Kassi, Narjes Nasiri-Ansari, Manpal S. Randeva, Nikolaos Nikiteas, Vanlata H. Patel, Athanasios G. Papavassiliou, Harpal S. Randeva, Georgios Dimitriadis, Ioannis D. Kostakis, Gregory Kaltsas
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	Blood Glucose 0301 basic medicine Apolipoprotein E medicine.medical_specialty RM Mice Knockout ApoE Administration Oral Hemodynamics Blood Pressure 030209 endocrinology & metabolism Inflammation Diet High-Fat Biochemistry 03 medical and health sciences 0302 clinical medicine Endocrinology Glucosides Diastole Heart Rate medicine.artery Internal medicine Hyperlipidemia medicine Empagliflozin Animals RNA Messenger Benzhydryl Compounds Molecular Biology Aorta business.industry Fasting Atherosclerosis medicine.disease Lipids Plaque Atherosclerotic Mice Inbred C57BL 030104 developmental biology Knockout mouse Metalloproteases Immunohistochemistry lipids (amino acids peptides and proteins) medicine.symptom business RC
ISSN:	0303-7207
Popis:	The effects of long-term treatment with empagliflozin on biochemical and immunohistochemical markers related to atherosclerosis and atherosclerosis development in the aorta of apolipoprotein E knockout [Apo-E (−/−)] mice were evaluated in this study. Empagliflozin-treated mice had lower total cholesterol (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82cb5411f2b79cd763fb5fd44942872b http://wrap.warwick.ac.uk/119049/1/WRAP-empagliflozin-improves-primary-haemodynamic-parameters-attenuates-development-atherosclerosis-high-fat-diet-fed-APOE-knockout-mice-Randeva-2019.pdf Zobrazit plný text záznamu Full Text from ScienceDirect