Sirolimus in the Management of Blue Rubber Bleb Nevus Syndrome: A Case Report and Review of the Literature

Autor:	Muhtadi Alghubayn, Nada Ghazi AlQadri, Bayan Musaed AlNooh, Saad Al-Ajlan
Rok vydání:	2021
Předmět:	medicine.medical_specialty Blood transfusion business.industry Anemia medicine.medical_treatment brbns Vascular malformation blue rubber bleb nevus syndrome Dermatology medicine.disease Gastroenterology Blue rubber bleb nevus syndrome vascular malformation sirolimus medicine.anatomical_structure Case and Review RL1-803 Internal medicine Sirolimus medicine Chronic gi bleeding Venous malformation business Subcutaneous tissue medicine.drug
Zdroj:	Case Reports in Dermatology, Vol 13, Iss 2, Pp 417-421 (2021) Case Reports in Dermatology
ISSN:	1662-6567
Popis:	Blue rubber bleb nevus syndrome (BRBNS) is a rare multifocal venous malformation (VM) that may affect any tissue or organ but mainly affects the skin, subcutaneous tissue and gastrointestinal (GI) tract. Patients present with serious anemia, treated with lifelong iron supplements and frequent blood transfusion secondary to chronic GI bleeding. Variable therapeutic modalities were used in the management of BRBNS; sirolimus (SRL), a mammalian target of rapamycin (mTOR) inhibitor, is found to be a promising therapy for vascular anomalies.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82c6fb5670f45a3c2bad976ea1263efa https://doi.org/10.1159/000511535 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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