Pituitary stalk compression by the dorsum sellae: possible cause for late childhood onset growth disorders
| Autor: | Hiroyuki Nakagawa, Toshiaki Taoka, Masahiko Sakamoto, Masayuki Fujioka, Shoichiro Otake, Kimihiko Kichikawa, Satoru Iwasaki, Shingo Okamoto, Shinji Hirohashi |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Adult
Male Aging endocrine system Pituitary gland Adolescent Statistics as Topic Biomedical Engineering Biophysics Short stature Dorsum sellae medicine Deformity Humans Radiology Nuclear Medicine and imaging Pituitary stalk compression Child Growth Disorders Retrospective Studies Pituitary stalk business.industry Infant Newborn Infant Anatomy Late childhood Magnetic Resonance Imaging Body Height medicine.anatomical_structure Stalk Child Preschool Growth Hormone Pituitary Gland Female medicine.symptom business |
| Zdroj: | Magnetic Resonance Imaging. 24:651-656 |
| ISSN: | 0730-725X |
| DOI: | 10.1016/j.mri.2005.12.015 |
| Popis: | Purpose: The purpose of this study was to evaluate the relationship between pituitary stalk compression by the dorsum sellae and clinical or laboratory findings in short stature children. Materials and Methods: We retrospectively reviewed magnetic resonance images of the pituitary gland and pituitary stalk for 34 short stature children with growth hormone (GH) deficiency and 24 age-matched control cases. We evaluated the degree of pituitary stalk compression caused by the dorsum sellae. Body height, GH level, pituitary height and onset age of the short stature were statistically compared between cases of pituitary stalk compression with associated stalk deformity and cases without compression. Results: Compression of the pituitary stalk with associated stalk deformity was seen in nine cases within the short stature group. There were no cases observed in the control group. There were no significant differences found for body height, GH level and pituitary height between the cases of pituitary stalk compression with associated stalk deformity and cases without compression. However, a significant difference was seen in the onset age between cases with and without stalk compression. Conclusion: Pituitary stalk compression with stalk deformity caused by the dorsum sellae was significantly correlated with late childhood onset of short stature. |
| Databáze: | OpenAIRE |
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