Surgical treatment of temporal lobe epilepsy and micro-neuroanatomical details of the medial temporal region
| Autor: | Onur Ozgural, Serdar Solmaz, Alain Wambe, Atilla Erdem, Umit Eroglu, Ozan Tekneci, Ayse Karatas Demirciler |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Drug Resistant Epilepsy medicine.medical_specialty Adolescent medicine.medical_treatment Temporal lobe Young Adult 03 medical and health sciences Epilepsy 0302 clinical medicine medicine Humans Epilepsy surgery Child Surgical treatment Anterior temporal lobectomy Aged Retrospective Studies business.industry Amygdalohippocampectomy Middle Aged Anterior Temporal Lobectomy medicine.disease Temporal Lobe Surgery Treatment Outcome Epilepsy Temporal Lobe Child Preschool Female Neurology (clinical) Neurosurgery Complication business 030217 neurology & neurosurgery |
| Zdroj: | Turkish Neurosurgery. |
| ISSN: | 1019-5149 |
| Popis: | AIM To evaluate the long-term efficacy of temporal lobe epilepsy (TLE) surgery, and to emphasize the factors affecting seizure outcomes such as surgical technique nuances and micro-neuroanatomical details in TLE cases. MATERIAL AND METHODS In this retrospective analysis, 238 patients who underwent epilepsy surgery at Ankara University (Faculty of Medicine, Department of Neurosurgery) between 1990 and 2019 were included. All patients presented with symptoms of TLE. They were divided into two groups: those with neoplastic lesions and those with non-neoplastic brain lesions presenting with medically intractable epilepsy. In the non-neoplastic group, the patients underwent anterior temporal lobectomy with amygdalohippocampectomy (ATL+AH), whereas in the neoplastic group, the patients underwent tumor resection in addition to ATL+AH. RESULTS This study included 126 female (52.9%) and 112 male (47.1%) patients. The mean duration of epilepsy was 14.65 ± 9.29 years (0.08?46 years). The number of patients in the non-neoplastic and neoplastic groups was 190 and 48, respectively. The mean duration of follow-up was 15.82 ± 6.55 years (1?28 years). In the neoplastic and non-neoplastic groups, the Engel I seizure-free rates were 91.6% (44/48) and 90.5% (172/190), respectively. Furthermore, no mortality was observed among the groups. CONCLUSION Overall, effective seizure control was achieved with acceptable morbidity and complication rates in the neoplastic and non-neoplastic groups with surgical and micro-neuroanatomical nuances. |
| Databáze: | OpenAIRE |
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