Neuroendocrine carcinoma arising from Barrett's esophageal adenocarcinoma: a case report
| Autor: | Shigenao Ishikawa, Takashi Yao, Tomoki Inaba, Koichi Izumikawa, Satoko Nakamura, Sakuma Takahashi, Kumiko Yamamoto, Ichiro Sakakihara, Masaki Wato, Tsubasa Kinoshita, Shigetomi Tanaka |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Pathology medicine.medical_specialty Esophageal Neoplasms Adenocarcinoma Lesion 03 medical and health sciences Barrett Esophagus 0302 clinical medicine Surgical oncology Biopsy medicine Humans Stage (cooking) Esophagus Aged medicine.diagnostic_test Esophagogastroduodenoscopy business.industry Gastroenterology General Medicine medicine.disease digestive system diseases Carcinoma Neuroendocrine medicine.anatomical_structure 030220 oncology & carcinogenesis Barrett's esophagus 030211 gastroenterology & hepatology Esophagoscopy medicine.symptom business |
| Zdroj: | Clinical journal of gastroenterology. 13(6) |
| ISSN: | 1865-7265 |
| Popis: | Neuroendocrine carcinoma in Barrett's esophagus is rare and its developmental mechanisms remain unclear. Neuroendocrine carcinoma arising in Barrett's esophagus with adenocarcinoma was detected at an early stage and resected by endoscopic submucosal dissection. Detailed pathological examination revealed that the neuroendocrine carcinoma originated via differentiation of the preexisting adenocarcinoma. A 79-year-old man presented with a flat protruding lesion in the esophagogastric junction. Esophagogastroduodenoscopy revealed a red flat 10-mm protruding lesion in the Barrett's epithelium and a shallow depression at the distal end. Narrow band imaging with magnification showed that the blood vessels in the protrusion were dilated and meandered irregularly, while those in the depression were small and did not form a network; the blood vessels were missing in some parts of the depression. Well-differentiated adenocarcinoma was diagnosed after analysis of the biopsy specimen of the protrusion, and endoscopic submucosal dissection was performed. The pathological diagnosis was neuroendocrine carcinoma with an adenocarcinoma component. |
| Databáze: | OpenAIRE |
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