A hybrid erbium(III)-bacteriochlorin near-infrared probe for multiplexed biomedical imaging
| Autor: | Ting Wang, Zhengxin Wang, Lingfei Lu, Yong Fan, Weimin Liu, Zuyang He, Hongxin Zhang, Ziyu Wang, Caixia Sun, Dongyuan Zhao, Fan Zhang, Peng Yu, Shangfeng Wang, Mengyao Zhao, Weian Zhang, Jean-Claude G. Bünzli, Zhiyong Liu |
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| Předmět: |
Porphyrins
Fluorophore Materials science chemistry.chemical_element amplification in-vivo Erbium chemistry.chemical_compound symbols.namesake Stokes shift Animals General Materials Science Image resolution Fluorescent Dyes complexes Spectroscopy Near-Infrared Quenching (fluorescence) dye business.industry Mechanical Engineering Near-infrared spectroscopy General Chemistry Condensed Matter Physics chemistry Mechanics of Materials symbols Optoelectronics Molecular imaging business Luminescence |
| Popis: | Spectrally distinct fluorophores are desired for multiplexed bioimaging. In particular, monitoring biological processes in living mammals needs fluorophores that operate in the 'tissue-transparent' near-infrared (NIR) window, that is, between 700 and 1,700 nm. Here we report a fluorophore system based on molecular erbium(III)-bacteriochlorin complexes with large Stokes shift (>750 nm) and narrowband NIR-to-NIR downconversion spectra (full-width at half-maximum An erbium(III)-bacteriochlorin probe with large Stokes shift and efficient near-infrared to near-infrared energy conversion enables multiplexed imaging of deep tissues in living animals. |
| Databáze: | OpenAIRE |
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