Operating procedures, risk management and challenges during implementation of adaptive and non-adaptive MR-guided radiotherapy: 1-year single-center experience

Autor: Cäcilia S. Reiner, Michael Mayinger, M. Chamberlain, Nicolaus Andratschke, M. Baumgartl, N. Weitkamp, C. Linsenmeier, Panagiotis Balermpas, Matea Pavic, Matthias Guckenberger, Stephanie Tanadini-Lang, Helena Garcia Schüler, L. Wilke, J. Krayenbühl
Přispěvatelé: University of Zurich
Rok vydání: 2021
Předmět:
Male
Organs at Risk
Quality Assurance
Health Care

Risk analysis
R895-920
Image-guided radiotherapy
Single Center
Medical physics. Medical radiology. Nuclear medicine
Neoplasms
Medicine
RC254-282
Risk management
Aged
80 and over

Contouring
SBRT
10042 Clinic for Diagnostic and Interventional Radiology
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Radiotherapy Dosage
Middle Aged
Prognosis
10044 Clinic for Radiation Oncology
Combined Modality Therapy
Oncology
Female
Online-adaptive radiotherapy
Adult
medicine.medical_specialty
Process (engineering)
610 Medicine & health
MR-guided radiotherapy
Radiosurgery
Re-Irradiation
Humans
Radiology
Nuclear Medicine and imaging

Medical physics
Aged
Retrospective Studies
Risk Management
Descriptive statistics
business.industry
Research
Patient Selection
Radiotherapy Planning
Computer-Assisted

Health Plan Implementation
Workflow
Radiotherapy
Intensity-Modulated

business
Quality assurance
Radiotherapy
Image-Guided
Zdroj: Radiation Oncology (London, England)
Radiation Oncology, Vol 16, Iss 1, Pp 1-10 (2021)
ISSN: 1748-717X
Popis: Background Main purpose was to describe procedures and identify challenges in the implementation process of adaptive and non-adaptive MR-guided radiotherapy (MRgRT), especially new risks in workflow due to the new technique. We herein report the single center experience for the implementation of (MRgRT) and present an overview on our treatment practice. Methods Descriptive statistics were used to summarize clinical and technical characteristics of treatment and patient characteristics including sites treated between April 2019 and end of March 2020 after ethical approval. A risk analysis was performed to identify risks of the online adaptive workflow. Results A summary of the processes on the MR-Linac including workflows, quality assurance and possible pitfalls is presented. 111 patients with 124 courses were treated during the first year of MR-guided radiotherapy. The most commonly treated site was the abdomen (42% of all treatment courses). 73% of the courses were daily online adapted and a high number of treatment courses (75%) were treated with stereotactic body irradiation. Only 4/382 fractions could not be treated due to a failing online adaptive quality assurance. In the risk analysis for errors, the two risks with the highest risk priority number were both in the contouring category, making it the most critical step in the workflow. Conclusion Although challenging, establishment of MRgRT as a routinely used technique at our department was successful for all sites and daily o-ART was feasible from the first day on. However, ongoing research and reports will have to inform us on the optimal indications for MRgRT because careful patient selection is necessary as it continues to be a time-consuming treatment technique with restricted availability. After risk analysis, the most critical workflow category was the contouring process, which resembles the need of experienced staff and safety check paths.
Databáze: OpenAIRE