Cobalt‐Catalysed Reductive Etherification Using Phosphine Oxide Promoters under Hydroformylation Conditions

Autor:	Fábio G. Delolo, Johannes Fessler, Helfried Neumann, Kathrin Junge, Eduardo N. dos Santos, Elena V. Gusevskaya, Matthias Beller
Rok vydání:	2022
Předmět:	Organic Chemistry General Chemistry Catalysis
Zdroj:	Chemistry – A European Journal. 28
ISSN:	1521-3765 0947-6539
Popis:	A phosphine-oxide-promoted, cobalt-catalysed reductive etherification using syngas as a reductant is reported. This novel methodology was successfully used to prepare a broad range of unsymmetrical ethers from various aldehydes and alcohols containing diverse functional groups, and was scaled-up to multigram scale under comparably mild conditions. Mechanistic experiments support an acetalization-hydrogenation sequence.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::829a344774f028d4b32defe0d3d023f3 https://doi.org/10.1002/chem.202103903 Zobrazit plný text záznamu Plný text