The effect of a dietary portfolio compared to a DASH-type diet on blood pressure
| Autor: | Jiri Frohlich, C. Pellini, Robert G. Josse, Balachandran Bashyam, Patrick Couture, Christopher Ireland, Lawrence A. Leiter, R. J. de Souza, Benoît Lamarche, Arash Mirrahimi, P. Galange, Cyril W. C. Kendall, Vanu Ramprasath, Viranda H. Jayalath, John L. Sievenpiper, Dorothea Faulkner, Peter B. Jones, L. S. A. Augustin, David J.A. Jenkins, Korbua Srichaikul, Stephanie K. Nishi |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Mean arterial pressure Canada Mediterranean diet Endocrinology Diabetes and Metabolism Diastole Medicine (miscellaneous) Hyperlipidemias Diet Mediterranean Diet Records Risk Assessment Plant protein Animal science Internal medicine Hyperlipidemia medicine Humans Diet Fat-Restricted Aged Nutrition and Dietetics business.industry Sodium Coronary heart disease risk Blood Pressure Determination Diet Sodium-Restricted Middle Aged Cardiovascular disease medicine.disease 3. Good health Blood pressure Endocrinology Treatment Outcome Cardiovascular Diseases Decreased blood pressure Hypertension Female Cardiology and Cardiovascular Medicine business Energy Intake Vegetable protein Follow-Up Studies |
| Zdroj: | Nutrition, metabolism, and cardiovascular diseases : NMCD. 25(12) |
| ISSN: | 1590-3729 |
| Popis: | Background and aim Compared to a DASH-type diet, an intensively applied dietary portfolio reduced diastolic blood pressure at 24 weeks as a secondary outcome in a previous study. Due to the importance of strategies to reduce blood pressure, we performed an exploratory analysis pooling data from intensively and routinely applied portfolio treatments from the same study to assess the effect over time on systolic, diastolic and mean arterial pressure (MAP), and the relation to sodium (Na + ), potassium (K + ), and portfolio components. Methods and results 241 participants with hyperlipidemia, from four academic centers across Canada were randomized and completed either a DASH-type diet (control n = 82) or a dietary portfolio that included, soy protein, viscous fibers and nuts (n = 159) for 24 weeks. Fasting measures and 7-day food records were obtained at weeks 0, 12 and 24, with 24-h urines at weeks 0 and 24. The dietary portfolio reduced systolic, diastolic and mean arterial blood pressure compared to the control by 2.1 mm Hg (95% CI, 4.2 to −0.1 mm Hg) (p = 0.056), 1.8 mm Hg (CI, 3.2 to 0.4 mm Hg) (p = 0.013) and 1.9 mm Hg (CI, 3.4 to 0.4 mm Hg) (p = 0.015), respectively. Blood pressure reductions were small at 12 weeks and only reached significance at 24 weeks. Nuts, soy and viscous fiber all related negatively to change in mean arterial pressure (ρ = −0.15 to −0.17, p ≤ 0.016) as did urinary potassium (ρ = −0.25, p = 0.001), while the Na + /K + ratio was positively associated (ρ = 0.20, p = 0.010). Conclusions Consumption of a cholesterol-lowering dietary portfolio also decreased blood pressure by comparison with a healthy DASH-type diet. Clinical Trial Reg. No. NCT00438425, clinicaltrials.gov. |
| Databáze: | OpenAIRE |
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