4,5-Disubstituted Pyridazin-3(2H)-ones as Hypotensive Drugs: Incorporation of a β-Blocking Moiety
Autor: | Félix Sánchez, Tomás Torres, Vicente Gómez-Parra, M. Carmen Gómez-Gil |
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Rok vydání: | 1986 |
Předmět: |
Chemical Phenomena
Stereochemistry medicine.drug_class Blocking (radio) Chemistry Adrenergic beta-Antagonists Hypotensive drug Pharmaceutical Science Carboxamide Biological activity Nuclear magnetic resonance spectroscopy Hypotensive Drugs Pyridazines Drug Discovery medicine Moiety Antihypertensive Agents |
Zdroj: | Archiv der Pharmazie. 319:60-64 |
ISSN: | 1521-4184 0365-6233 |
DOI: | 10.1002/ardp.19863190112 |
Popis: | The synthesis of the biologically active 4,5-disubstituted pyridazin-3(2H)-ones 6 and 7 starting from the 4,5-Dihalopyridazinones 2 is described. |
Databáze: | OpenAIRE |
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