Natural History of Left Ventricular Function in Patients With Uncomplicated Acute Myocardial Infarction
| Autor: | Tetsuro Sugiura, Mitsuo Inada, Toshiji Iwasaka, Hisako Tsuji, Naohiko Ohkubo, Seishi Nakamura |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine medicine.medical_specialty Time Factors Myocardial Infarction Hemodynamics Coronary Disease Anterior myocardial infarction Coronary Angiography Critical Care and Intensive Care Medicine Ventricular Function Left Internal medicine Humans Medicine In patient Myocardial infarction Radionuclide angiocardiography Aged Ejection fraction Ventricular function business.industry Gated Blood-Pool Imaging Heart Stroke Volume Middle Aged medicine.disease Natural history Cardiology Cardiology and Cardiovascular Medicine business |
| Zdroj: | Chest. 103:1320-1324 |
| ISSN: | 0012-3692 |
| Popis: | To investigate the serial changes of the infarcted and the noninfarcted areas, first-pass radionuclide angiocardiography was performed in 16 patients with uncomplicated anterior myocardial infarction (MI) at four weeks, one year, and two years after the onset of MI. Global ejection fraction (EF) and regional EF of the infarcted area improved significantly from four weeks to one year after MI (from 39 +/- 16 to 44 +/- 16 percent, 23 +/- 3 to 29 +/- 5 percent, both p0.01), but did not change from one year to two years after MI. Regional EF of the noninfarcted area and left ventricular end-diastolic and end-systolic volume did not change during the study period. There was a significant relation in the direction of the changes of global EF and regional EF of the infarcted area during the first year after MI, whereas no relation was observed between the changes of global EF and regional EF of the noninfarcted area. A greater improvement in regional EF of the infarcted area was observed in seven patients who had spontaneous recanalization compared with nine patients with totally occluded coronary arteries. Thus, a significant improvement in cardiac function, mainly due to the increase in regional EF of the infarcted area, was observed during the first year after MI, which was related to patency of coronary artery. |
| Databáze: | OpenAIRE |
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