Mortality and Morbidity in Premature Infants: An East and West Comparative Study
| Autor: | Saikiran Deshabhotla, Joseph Hagan, Srinivas Murki, Venkateshwarlu Vardhelli, Monika Patil |
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| Rok vydání: | 2021 |
| Předmět: |
Pediatrics
medicine.medical_specialty Birth weight Gestational Age Infant Premature Diseases Infant Newborn Diseases Odds 03 medical and health sciences 0302 clinical medicine Adrenal Cortex Hormones Pregnancy 030225 pediatrics Infant Mortality medicine Hospital discharge Humans 030212 general & internal medicine Child Bronchopulmonary Dysplasia Retrospective Studies business.industry Infant Newborn Obstetrics and Gynecology Gestational age Infant Retrospective cohort study Odds ratio medicine.disease Confidence interval Pediatrics Perinatology and Child Health Small for gestational age Female Morbidity business Infant Premature |
| Zdroj: | American journal of perinatology. 39(13) |
| ISSN: | 1098-8785 |
| Popis: | Objective Survival of preterm infants differs dramatically depending on birthplace. No previous studies have compared outcomes of preterm infants between low middle-income and high-income countries such as India and the United States. The purpose of this study is to evaluate differences in care practices, resources, mortality, and morbidities in preterm infants with birth weight 700 to 1,500 g between two major neonatal centers in these countries. Study Design This is a retrospective cohort study with de-identified data from Fernandez Hospital (FH) in Hyderabad, India, and Texas Children's Hospital (TCH) in Houston, TX, for infants born January 2016 to December 2018, and weighing 700 to 1,500 g at birth. The primary outcome was death before hospital discharge. Results Of 1,195 infants, 736 were admitted to FH and 459 were admitted to TCH. After controlling for differences in gestational age, small for gestational age, and antenatal corticosteroid use, TCH patients had lower mortality before hospital discharge (adjusted odds ratio [aOR] = 0.28, 95% confidence interval [CI]: 0.16–0.48, p Conclusion In this study, TCH infants had decreased odds of death before hospital discharge compared with FH but higher odds of BPD, which may be related to increased survival and differences in care practices. Key Points |
| Databáze: | OpenAIRE |
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