The Identity of 'Chromium Malate'
| Autor: | Megan Smart, Silas Brown, Molly M. Lockart, Michael K. Bowman, Haley Tannehill, John B. Vincent |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Electron paramagnetic resonance spectroscopy Spectrometry Mass Electrospray Ionization Future studies Endocrinology Diabetes and Metabolism Clinical Biochemistry Malates chemistry.chemical_element 010501 environmental sciences 01 natural sciences Biochemistry Inorganic Chemistry 03 medical and health sciences Chromium Identity (mathematics) Chromium Compounds Organic chemistry Molecule 0105 earth and related environmental sciences chemistry.chemical_classification 030109 nutrition & dietetics Biochemistry (medical) General Medicine Polymer Crystallography chemistry Spectrophotometry |
| Zdroj: | Biological Trace Element Research. 181:369-377 |
| ISSN: | 1559-0720 0163-4984 |
| DOI: | 10.1007/s12011-017-1046-7 |
| Popis: | Recently, several studies on the effects of a compound named “chromium malate,” with the proposed formula “Cr2malate3·xH2O” where x = 3.5 or 5, on the health of healthy and diabetic rats have appeared. However, the compound is poorly characterized, and knowing the identity of this material could be important in the interpretation of the previous and of future studies on the effects of this compound in animals. Consequently, the synthesis, characterization, and identity of this material were explored. A combination of spectroscopic, magnetic, and elemental analyses and mass spectral studies reveal that the compound is probably a polymer, not a discrete molecule, and does not have the composition previously reported. The repeating unit of the polymer possesses an antiferromagnetically coupled trinuclear Cr(III) core. The current study suggests that previous reports on chromium malate and its effects in animals must be viewed with caution. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink