Gut microbiota associations with metabolic syndrome and relevance of its study in pediatric subjects
| Autor: | Tomás García-Cayuela, Carolina Senés-Guerrero, Carmen Hernández-Brenes, Ana K. Carrizales-Sánchez |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Microbiology (medical)
Pediatric Obesity microbial metabolites school-age children microbiome Review RC799-869 Gut flora Bioinformatics Microbiology digestive system Childhood obesity metabolic syndrome medicine Humans Relevance (information retrieval) Microbiome Child pediatric subjects Bacteria biology gut microbiota Gastroenterology Feeding Behavior Diseases of the digestive system. Gastroenterology medicine.disease biology.organism_classification Gastrointestinal Microbiome Infectious Diseases Diabetes Mellitus Type 2 Dysbiosis sense organs Metabolic syndrome |
| Zdroj: | Gut Microbes, Vol 13, Iss 1 (2021) Gut Microbes article-version (VoR) Version of Record |
| ISSN: | 1949-0984 1949-0976 |
| Popis: | Childhood obesity and T2DM have shown a recent alarming increase due to important changes in global lifestyle and dietary habits, highlighting the need for urgent and novel solutions to improve global public health. Gut microbiota has been shown to be relevant in human health and its dysbiosis has been associated with MetS, a health condition linked to the onset of relevant diseases including T2DM. Even though there have been recent improvements in the understanding of gut microbiota–host interactions, pediatric gut microbiota has been poorly studied compared to adults. This review provides an overview of MetS and its relevance in school-age children, discusses gut microbiota and its possible association with this metabolic condition including relevant emerging gut microbiome-based interventions for its prevention and treatment, and outlines future challenges and perspectives in preventing microbiota dysbiosis from the early stages of life. |
| Databáze: | OpenAIRE |
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