Cytokines, adipocytokines and inflammatory markers in patients on continuous ambulatory peritoneal dialysis and hemodialysis

Autor: Suleyman Turk, Beyhan Baltaci, Seval Akbulut, Mustafa Keles, Türkan Toka Özer, Mufide Oncel, Aysel Kiyici
Přispěvatelé: Selçuk Üniversitesi
Rok vydání: 2016
Předmět:
Adult
Leptin
Male
medicine.medical_specialty
medicine.medical_treatment
030232 urology & nephrology
Adipokine
continuous ambulatory peritoneal dialysis
Enzyme-Linked Immunosorbent Assay
Inflammation
030204 cardiovascular system & hematology
Critical Care and Intensive Care Medicine
Gastroenterology
03 medical and health sciences
0302 clinical medicine
Immune system
Adipokines
Peritoneal Dialysis
Continuous Ambulatory
Renal Dialysis
Internal medicine
medicine
Humans
Adipocytokines
Aged
hemodialysis
Interleukin-6
Tumor Necrosis Factor-alpha
business.industry
Continuous ambulatory peritoneal dialysis
General Medicine
Middle Aged
Ghrelin
hsCRP
C-Reactive Protein
Endocrinology
Nephrology
Cytokines
Kidney Failure
Chronic
Female
Tumor necrosis factor alpha
Hemodialysis
medicine.symptom
business
Biomarkers
Zdroj: Renal Failure. 38:1071-1075
ISSN: 1525-6049
0886-022X
DOI: 10.1080/0886022x.2016.1193874
Popis: WOS: 000382175000008
PubMed: 27267129
Background: Cytokines are essential mediators of immune response. Chronic renal failure patients suffer from chronic inflammation that results from factors such as impaired renal function, accumulation of uremic toxins and bio incompatibility of dialyzer membranes. These patients are also at increased risk of cardiovascular diseases. We have evaluated cytokines, adipocytokines and inflammatory markers in patients with chronic renal failure undergoing hemodialysis (HD) and continuous ambulatory peritoneal dialysis (CAPD).Material and methods: We have determined serum tumor necrosis factor- (TNF-), interleukin-6 (IL-6), high-sensitivity C-reactive protein (hsCRP), leptin and ghrelin levels of chronic renal failure patients treated with either HD (n=20) or CAPD (n=20). TNF-, IL-6, ghrelin and leptin measurements were performed by commercially available kits based on enzyme-linked immunosorbent assay (ELISA) method. hsCRP levels were determined by turbidimetric methods.Results: Serum TNF- and IL-6 levels of patients on HD were significantly higher than those of the ones on CAPD (p
Databáze: OpenAIRE
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