Renal biopsy in a patient with haemophilia A and cryoglobulinaemic membranoproliferative glomerulonephritis associated with hepatitis C virus infection
Autor: | Ayako Nishihira, Kaname Hirowatari, Eiji Ishimura, Takao Tsuchida, Hideaki Shima, Yoshiki Nishizawa, Kenichi Wakasa, Masaaki Inaba, Katsuhito Mori, Ikue Kobayashi, Kaori Shidara |
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Jazyk: | angličtina |
Rok vydání: | 2009 |
Předmět: |
hepatitis C virus
medicine.medical_specialty Hepatitis C virus membranoproliferative glomerulonephritis Haemophilia A Case Report haemophilia A medicine.disease_cause Haemophilia Gastroenterology chemistry.chemical_compound renal biopsy Internal medicine hemic and lymphatic diseases Membranoproliferative glomerulonephritis medicine Transplantation medicine.diagnostic_test business.industry Ribavirin Hepatitis C medicine.disease chemistry Nephrology Immunology Prednisolone Renal biopsy business medicine.drug |
Zdroj: | NDT Plus |
ISSN: | 1753-0792 1753-0784 |
Popis: | A renal biopsy was performed in a 47-year-old man with haemophilia A. Thirty minutes after administration of an intravenous bolus of 4000 units of recombinant factor VIII, which increased the activity to 74–91%, a needle renal biopsy was successfully performed, followed by administration of 3000 units of factor VIII in the evening, and then the subsequent morning and evening. The patient was diagnosed with hepatitis C virus-associated membranoproliferative glomerulonephritis. Treatment with interferon, ribavirin, prednisolone and cyclosporine A improved the nephrotic syndrome. This is the first report of a successful renal biopsy in a patient with haemophilia A after factor VIII injection. |
Databáze: | OpenAIRE |
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