Patterns of failure of bulky-barrel carcinomas of the cervix
| Autor: | Richard J. Stock, Donald G. Gallup, Hugh D. Wolcott, Deborah L. Coleman, Luther B. Otken |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Adult
medicine.medical_specialty medicine.medical_treatment Brachytherapy Uterine Cervical Neoplasms Hysterectomy Postoperative Complications medicine Humans Neoplasm Metastasis Cervix Aged Neoplasm Staging Retrospective Studies Cervical cancer Vaginal Smears business.industry Carcinoma Obstetrics and Gynecology Retrospective cohort study General Medicine Middle Aged medicine.disease Combined Modality Therapy Survival Analysis Surgery Radiation therapy Bowel obstruction medicine.anatomical_structure Rectovaginal fistula Vaginal vault Female Neoplasm Recurrence Local business |
| Zdroj: | American journal of obstetrics and gynecology. 166(3) |
| ISSN: | 0002-9378 |
| Popis: | OBJECTIVE(S: This retrospective study was conducted to analyze the hypothesis that radiation therapy followed by extrafascial hysterectomy would improve survival in patients with bulky-barrel cervical carcinomas. STUDY DESIGN: Forty-three patients with bulky-barrel carcinomas of the cervix were treated over a 14-year period. The majority of these were treated with approximately 4000 cGY external beam, followed by brachytherapy, followed by extrafascial hysterectomy. RESULTS: Forty-seven percent of all patients are dead of disease; 2.3% are alive with disease. Of the total patients, 35% had diseased paraaortic nodes, and 80% of these are dead of disease. Of the patients dead of disease, 80% had distant metastases. Delayed complications included: vesicovaginal fistulas ( n = 3), surgery for bowel obstruction ( n = 3), rectovaginal fistula ( n = 1), and vaginal vault necrosis ( n = 3). CONCLUSION: These data do not support an improvement in survival of patients with bulky-barrel—shaped lesions treated with irradiation plus adjunctive hysterectomy. |
| Databáze: | OpenAIRE |
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