Prognostic factors in metastatic gastric carcinoma
Autor: | W. Ben Kridis, Jamel Daoud, G. Marrekchi, R. Mzali, Afef Khanfir |
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Rok vydání: | 2019 |
Předmět: |
Oncology
Adult Male Cancer Research medicine.medical_specialty Multivariate analysis medicine.medical_treatment Antineoplastic Agents Metastasis 03 medical and health sciences 0302 clinical medicine Gastrectomy Stomach Neoplasms Internal medicine Antineoplastic Combined Chemotherapy Protocols medicine Humans Neoplasm Metastasis Aged Retrospective Studies Univariate analysis Chemotherapy Performance status business.industry Incidence (epidemiology) Cancer Retrospective cohort study Middle Aged medicine.disease Prognosis Combined Modality Therapy 030220 oncology & carcinogenesis Female Fluorouracil Cisplatin business |
Zdroj: | Experimental oncology. 41(2) |
ISSN: | 1812-9269 |
Popis: | Although its incidence has declined over last half-century, gastric cancer remains the second most frequent cause of cancer death in the world. The ⅔ of the patients are metastatic at diagnosis. The current study aimed to identify some determinants of survival in patients with metastatic gastric carcinoma. MATERIALS AND METHODS It was a retrospective study that involved 49 patients treated with palliative chemotherapy between January 2000 and December 2010. Factors included: age, gender, performance status, metastatic diagnosis onset (at diagnosis or later); specific metastatic sites, number of metastatic localizations, response to chemotherapy, and hemoglobin rate. RESULTS In univariate analysis, factors associated to a better survival were: metastasis at diagnosis, good performance status, response to chemotherapy and single metastatic site. Independent factors in multivariate analysis were: metastasis at diagnosis and single metastatic site. CONCLUSION Our study confirmed many determinants on survival described in the literature. |
Databáze: | OpenAIRE |
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