Prognostic factors in metastatic gastric carcinoma

Autor: W. Ben Kridis, Jamel Daoud, G. Marrekchi, R. Mzali, Afef Khanfir
Rok vydání: 2019
Předmět:
Zdroj: Experimental oncology. 41(2)
ISSN: 1812-9269
Popis: Although its incidence has declined over last half-century, gastric cancer remains the second most frequent cause of cancer death in the world. The ⅔ of the patients are metastatic at diagnosis. The current study aimed to identify some determinants of survival in patients with metastatic gastric carcinoma. MATERIALS AND METHODS It was a retrospective study that involved 49 patients treated with palliative chemotherapy between January 2000 and December 2010. Factors included: age, gender, performance status, metastatic diagnosis onset (at diagnosis or later); specific metastatic sites, number of metastatic localizations, response to chemotherapy, and hemoglobin rate. RESULTS In univariate analysis, factors associated to a better survival were: metastasis at diagnosis, good performance status, response to chemotherapy and single metastatic site. Independent factors in multivariate analysis were: metastasis at diagnosis and single metastatic site. CONCLUSION Our study confirmed many determinants on survival described in the literature.
Databáze: OpenAIRE
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