Impact of Surgical Route in Influencing the Risk of Lymphatic Complications After Ovarian Cancer Staging
| Autor: | Antonino Ditto, Francesco Raspagliesi, Umberto Leone Roberti Maggiore, Cono Scaffa, Fabio Martinelli, Valentina Chiappa, Mauro Signorelli, Giorgio Bogani, Domenica Lorusso, Luca Montanelli, Violante Di Donato, Carmelo Infantino, Stefania Perotto, Chiara Borghi |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Lymphorrhea Staging Laparoscopy Lymphoceles Ovarian cancer Obstetrics and Gynecology Lymphocele Carcinoma Ovarian Epithelial Lower risk 03 medical and health sciences Postoperative Complications 0302 clinical medicine medicine Humans Minimally Invasive Surgical Procedures Neoplasms Glandular and Epithelial Lymphatic Diseases Lymphatic Vessels Neoplasm Staging Ovarian Neoplasms 030219 obstetrics & reproductive medicine medicine.diagnostic_test business.industry Odds ratio medicine.disease Confidence interval Surgery Lymphatic disease Lymphatic system 030220 oncology & carcinogenesis Lymph Node Excision Female Lymph Nodes business |
| Zdroj: | Journal of Minimally Invasive Gynecology. 24:739-746 |
| ISSN: | 1553-4650 |
| Popis: | Lymphatic complications are a common occurrence after staging surgery for early-stage ovarian cancer (eEOC). We investigated whether the introduction of minimally invasive surgery influences the risk of developing lymphoceles and lymphorrhea in patients undergoing staging for eEOC. For this purpose, data of consecutive patients affected by eEOC undergoing staging surgery between January 1980 and January 2016 were retrospectively reviewed, and a systematic review and meta-analysis was performed. This systematic review was registered in the International Prospective Register of Systematic Review. Among 341 patients included in the present study, 47 severe postoperative complications occurred (13.7%), including 40 lymphatic complications: 31 symptomatic lymphoceles (9%) and 9 cases of lymphorrhea (2.6%), respectively. Laparoscopic staging correlated with a lower risk of developing any severe lymphatic complications in comparison with open surgery (p = .02). In particular, the laparoscopic approach and para-aortic node involvement were associated with a trend toward lower lymphoceles (odds ratio, .13; 95% confidence interval, .07-2.20; p = .05) and a trend toward higher risk of lymphorrhea developing (odds ratio, 4.02; 95% confidence interval, .93-17.3; p = .06), respectively. In conclusion, the implementation of a minimally invasive approach might result in a slight reduction of lymphatic complications after eEOC staging. |
| Databáze: | OpenAIRE |
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