Clinical and cardiovascular alterations produced by scorpion envenomation in dogs
Autor: | Michiko Sakate, P. R. Cuyumjian, V. Fernandes, F. F. Cordeiro |
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Přispěvatelé: | Universidade Estadual Paulista (Unesp) |
Jazyk: | angličtina |
Rok vydání: | 2006 |
Předmět: |
dogs
Tityus serrulatus Sneeze lcsh:Arctic medicine. Tropical medicine lcsh:RC955-962 Venom Toxicology scorpion lcsh:RA1190-1270 lcsh:Zoology medicine lcsh:QL1-991 Envenomation lcsh:Toxicology. Poisons Scorpion toxin biology Scorpiones Hyperesthesia Canis familiaris biology.organism_classification Infectious Diseases Blood pressure Anesthesia Vomiting cardiopulmonary alterations Animal Science and Zoology Parasitology medicine.symptom |
Zdroj: | Journal of Venomous Animals and Toxins including Tropical Diseases, Volume: 12, Issue: 1, Pages: 19-43, Published: 2006 Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 12, Iss 1, Pp 19-43 (2006) Journal of Venomous Animals and Toxins including Tropical Diseases v.12 n.1 2006 The Journal of venomous animals and toxins including tropical diseases Universidade Estadual Paulista (UNESP) instacron:UNESP Scopus Repositório Institucional da UNESP |
Popis: | Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:21:51Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:45:38Z : No. of bitstreams: 1 2-s2.0-33645888428.pdf: 546909 bytes, checksum: c1c043e9d62b74a3ff65a363b3b1b143 (MD5) Made available in DSpace on 2014-05-27T11:21:51Z (GMT). No. of bitstreams: 0 Previous issue date: 2006-04-26 Scorpionism is a common problem that occurs in tropical and subtropical countries and assumes great medical-sanitary importance due to its fatal effect on sensitive individuals, being able to lead children and aged people to death. The envenomation lethal potential is responsible for the serious cardiopulmonary alterations the scorpion toxin produces in its victims. The present research evaluated the effects of Tityus serrulatus venom on dogs, using two distinct doses: a dose that simulates natural envenomation (0.4 mg/total dose), and an experimental dose (0.25 mg/kg). General clinical signs were observed at different moments after envenomation, and specific data related to the cardiopulmonary system were evaluated by systemic arterial pressure measurement, CK-MB enzymatic activity dosage, and radiographic, electrocardiographic and echocardiographic examinations. Results demonstrated that the scorpion venom, in experimental doses, was able to cause acute and reversible cardiac injury in few days, and, in the dose that simulated natural accident, it produced clinical signs of light envenomation, such as local pain, hyperesthesia, sialorrhea, vomiting, diarrhea, sneeze and prostration. Department of Clinical Veterinary Medicine School of Veterinary Medicine and Animal Husbandry São Paulo State University, Botucatu, São Paulo Clinical Laboratory School of Veterinary Medicine and Animal Husbandry São Paulo State University, Botucatu, São Paulo Veterinary Diagnostic, São Paulo Departamento de Clínica Veterinária Faculdade de Medicina Veterinária e Zootecnia UNESP, Distrito de Rubião Jr., s/n, 18.618-000, Botucatu, SP Department of Clinical Veterinary Medicine School of Veterinary Medicine and Animal Husbandry São Paulo State University, Botucatu, São Paulo Clinical Laboratory School of Veterinary Medicine and Animal Husbandry São Paulo State University, Botucatu, São Paulo Departamento de Clínica Veterinária Faculdade de Medicina Veterinária e Zootecnia UNESP, Distrito de Rubião Jr., s/n, 18.618-000, Botucatu, SP |
Databáze: | OpenAIRE |
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