Diagnostic value analysis of combined detection of Trx, CYFRA21-1 and SCCA in lung cancer
| Autor: | Ai-Jun Li, Bo Liu, Tao Qu, Jingwen Zhang, Ai-Ling Liu, Huaping Tang, Mei-Xiang Li, Ning Xu |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Cancer Research medicine.medical_specialty CYFRA21-1 Gastroenterology SCCA 03 medical and health sciences Cytokeratin 0302 clinical medicine Internal medicine Trx medicine Stage (cooking) Lung cancer Oncogene Receiver operating characteristic business.industry Cancer Articles medicine.disease Squamous carcinoma lung cancer 030104 developmental biology Oncology 030220 oncology & carcinogenesis Adenocarcinoma diagnostic value business |
| Zdroj: | Oncology Letters |
| ISSN: | 1792-1082 1792-1074 |
| Popis: | The expression levels of thioredoxin (Trx), cytokeratin fragment 21-1 (CYFRA21-1) and serum squamous cell carcinoma antigen (SCCA) in patients with lung cancer and the diagnostic value of combined detection were investigated. Sixty-five patients with lung cancer in Weihai Municipal Hospital from January 2014 to June 2017 were retrospectively selected as the observation group, while 60 healthy subjects receiving physical examination were selected as the control group. The expression levels of serum Trx, CYFRA21-1 and SCCA were detected. The sensitivity and specificity of single detection and combined detection of these indexes were compared. Moreover, the diagnostic values of single detection and combined detection were analyzed using the receiver operating characteristic (ROC) curve. The levels of CYFRA21-1 and SCCA were the highest in squamous carcinoma (P |
| Databáze: | OpenAIRE |
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