Pulmonary Mycobacterium parascrofulaceum Infection as an Immune Reconstitution Inflammatory Syndrome in an AIDS Patient
| Autor: | Daisuke Tasato, Futoshi Higa, Kenji Hibiya, Shinji Maeda, Shusaku Haranaga, Jiro Fujita, Yuichiro Tamaki, Masao Tateyama, Seiya Kato, Yuko Kazumi, Tsuneo Hirayasu, Hiromitsu Teruya, Tomonori Furugen, Hideta Nakamura |
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| Rok vydání: | 2010 |
| Předmět: |
Adult
Male Mycobacterium Acquired immunodeficiency syndrome (AIDS) Immune reconstitution inflammatory syndrome Immune Reconstitution Inflammatory Syndrome Levofloxacin Antiretroviral Therapy Highly Active Clarithromycin Internal Medicine medicine Humans Mycobacterium parascrofulaceum Respiratory Tract Infections Acquired Immunodeficiency Syndrome Mycobacterium Infections AIDS-Related Opportunistic Infections biology business.industry General Medicine biology.organism_classification medicine.disease Antiretroviral therapy Immunology business Rifampicin medicine.drug |
| Zdroj: | Internal Medicine. 49:1817-1821 |
| ISSN: | 1349-7235 0918-2918 |
| DOI: | 10.2169/internalmedicine.49.3616 |
| Popis: | Nontuberculous mycobacterial (NTM) infection in HIV (human immunodeficiency virus)-infected patients who have started highly active antiretroviral therapy (HAART) is well known to be one scenario of immune reconstitution inflammatory syndrome (IRIS). We encountered the first case in Japan of an HIV-infected patient with pulmonary Mycobacterium parascrofulaceum infection as IRIS. A 34 year-old man with acquired immunodeficiency syndrome (AIDS) was receiving highly active antiretroviral therapy. Lymphadenopathy was observed at the left pulmonary hilum. IRIS was suspected and thoracoscopic surgery was performed to diagnose the cause of lymphadenopathy. Granulomas were observed histologically, and M. parascrofulaceum was cultured. This organism was susceptible to Clarithromycin, rifampicin and levofloxacin. After the operation and without treatment, recurrence of M. parascrofulaceum infection was not observed. M. parascrofulaceum was isolated from several clinical specimens for the first time in 2004. To date, only five cases have been reported. |
| Databáze: | OpenAIRE |
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