Real-world outcomes of observation and treatment in diabetic macular edema with very good visual acuity: the OBTAIN study

Autor: Jay Chhablani, Jan Darius Unterlauft, Zafer Cebeci, Dinah Zur, Matias Iglicki, Inês Laíns, Mali Okada, Anna Sala-Puigdollers, Catharina Busch, Anat Loewenstein, Voraporn Chaikitmongkol, Ana Rita Santos, Marco Lupidi, Paradee Kunavisarut, Patricio J. Rodríguez-Valdés, Matus Rehak, Samantha Fraser-Bell, Adrian T. Fung, Pierre-Henry Gabrielle, Assaf Hilely, Małgorzata Ozimek, Ermete Giancipoli
Přispěvatelé: Laboratoire LTEE, University of Sydney, Tel-Aviv Sourasky Medical Center, Tecnológico de Monterrey (ITESM), Istanbul University, Università degli Studi di Perugia (UNIPG), Westmead Hospital [Sydney], Macquarie University, Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA), Institut National de la Recherche Agronomique (INRA)-Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), Université Bourgogne Franche-Comté [COMUE] (UBFC), Università degli Studi di Sassari, Chiang Mai University (CMU), Royal Melbourne Hospital, Universidade de Coimbra, Association for Innovation and Biomedical Research on Light and Image (AIBILI), Harvard Medical School [Boston] (HMS), Polytechnic Institute of Porto, Hospital Clínic de Barcelona, L.V. Prasad Eye Institute, Partenaires INRAE, Medical University in Lublin, National University of Central Buenos Aires, Retina Australia, Retina Pigmentosa ASBL, Retina Brazil, The Foundation Fighting Blindness, Retina Ry / Retina Finland, Association RETINA France, PRO RETINA Deutschland e. V., Hellenic Retina Society, Hong Kong, For Our Sight Foundation, Blindrafélagið, Icelandic Association of the visually impaired (BIAVI) (Retina Iceland), Blindrafelagid – Retina Iceland, Fighting Blindness, Certo Clav, Retina Itialia, Japanese Retinitis Pigmentosa Society, Patientengroep Retina, Retina New Zealand Inc., Retinitis Pigmentosa Foreningen i Norge, Pakistan Foundation Fighting Blindness, ARP (Portuguese Association of RP), Retina South Africa, Svenska RP-Föreningen, RETINITIS PIGMENTOSA TAIPEI, RP Fighting Blindness, Foundation Fighting Blindness, Repositório Científico do Instituto Politécnico do Porto, Busch, Catharina
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Male
Visual acuity
genetic structures
patient diabétique
Endocrinology
Diabetes and Metabolism
Visual Acuity
Angiogenesis Inhibitors
Observation
oedème maculaire
030204 cardiovascular system & hematology
Cohort Studies
0302 clinical medicine
Endocrinology
Good visual acuity
Diabetic macular edema
acuité visuelle
Real world outcomes
General Medicine
Middle Aged
[SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism
Prognosis
Bevacizumab
Treatment Outcome
Intravitreal Injections
Endocrinologie et métabolisme
Female
Original Article
medicine.symptom
Tomography
Optical Coherence
Cohort study
medicine.medical_specialty
Vision Disorders
Médecine humaine et pathologie
030209 endocrinology & metabolism
Macular Edema
03 medical and health sciences
Macular laser
Ophthalmology
Diabetes mellitus
Internal Medicine
medicine
Humans
Anti-VEGF therapy
Aged
Retrospective Studies
Endocrinology and metabolism
Diabetic Retinopathy
Dose-Response Relationship
Drug
business.industry
Intravitreal therapy
medicine.disease
eye diseases
laser
Human health and pathology
sense organs
Subretinal fluid
business
[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
thérapie
Zdroj: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Acta Diabetologica
Acta Diabetologica, Springer Verlag, 2019, 56 (7), pp.777-784. ⟨10.1007/s00592-019-01310-z⟩
Acta Diabetologica 7 (56), 777-784. (2019)
ISSN: 0940-5429
1432-5233
DOI: 10.1007/s00592-019-01310-z⟩
Popis: Aims To describe and compare the functional and anatomical outcomes of untreated and treated diabetic macular edema (DME) in eyes with very good baseline visual acuity (VA) in a real-world setting. Methods A 12-month, retrospective, multicenter, observational cohort study, including DME patients with baseline visual acuity (VA) ≤ 0.1 logMAR (≥ 20/25 Snellen) and central subfield thickness (CST) > 250 µm with intra- and/or subretinal fluid seen on optical coherence tomography. Results A total of 249 eyes were included, of which 155 were treated and 94 were non-treated during follow-up. Most eyes maintained vision (VA gain or VA loss
Databáze: OpenAIRE
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