Widespread cutaneous necrosis and antiphospholipid antibodies: two episodes related to surgical manipulation and urinary tract infection
| Autor: | Ana Sáez, C. Soria, C. Schoendorff, L.F. Del Castillo, C. Garcia Garcia, A.Rodriguez Alen, S. Urrutia, N. Diez-Caballero, D. Garcia Almagro |
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| Rok vydání: | 1997 |
| Předmět: |
Pathology
medicine.medical_specialty Necrosis medicine.drug_class Urinary system Dermatology Postoperative Complications immune system diseases Antiphospholipid syndrome Recurrence Immunopathology medicine Humans skin and connective tissue diseases Urinary Tract Skin Lupus anticoagulant Systemic lupus erythematosus business.industry Anticoagulant Middle Aged medicine.disease Antiphospholipid Syndrome Antibodies Anticardiolipin Lupus Coagulation Inhibitor Urinary Tract Infections Female medicine.symptom Urinary tract obstruction business |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 0190-9622 |
| Popis: | Widespread cutaneous necrosis (WCN) associated with antiphospholipid antibodies is rare. Its mechanisms have yet to be elucidated, and there are no well-established guidelines for its management. We describe a woman who had two episodes of WCN related to surgical manipulation for urinary tract obstruction and urinary tract infection. Lupus anticoagulant was always positive. In the second episode anticardiolipin antibodies were elevated, and protein C levels were temporarily decreased. We found only ten previously reported cases of WCN associated with antiphospholipid antibodies, none of which were related to surgical manipulation. |
| Databáze: | OpenAIRE |
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