Serum triglycerides and risk for death in Stage 3 and Stage 4 chronic kidney disease
| Autor: | Martin J. Schreiber, Stacey E. Jolly, Mark J. Sarnak, Jesse D. Schold, Sankar D. Navaneethan, George Thomas, Joseph V. Nally, Susana Arrigain, Emilio D. Poggio |
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| Rok vydání: | 2012 |
| Předmět: |
Male
medicine.medical_specialty Population Renal function Gastroenterology Cohort Studies chemistry.chemical_compound Risk Factors Internal medicine medicine Humans Registries Renal Insufficiency Chronic education Triglycerides Survival analysis Aged Ohio Proportional Hazards Models Aged 80 and over Transplantation education.field_of_study Triglyceride business.industry Proportional hazards model Hazard ratio Age Factors Middle Aged Clinical Science medicine.disease Endocrinology chemistry Nephrology Female Stage 4 chronic kidney disease business Kidney disease |
| Zdroj: | Nephrology Dialysis Transplantation. 27:3228-3234 |
| ISSN: | 1460-2385 0931-0509 |
| Popis: | Background. An elevated triglyceride level is associated with cardiovascular and all-cause mortality in the general population. The associations between serum triglyceride and all-cause mortality among patients with chronic kidney disease (CKD) are unclear. Methods. Patients with Stage 3 and Stage 4 CKD (estimated glomerular filtration rate 15–59 mL/min/1.73 m 2 ) who had serum triglycerides measured prior to being classified as CKD were included. We examined the associations of serum triglyceride levels with all-cause mortality among 25 641 Stage 3 and Stage 4 CKD patients using Cox proportional hazard models and Kaplan–Meier survival curves. Results. In the Cox model, after adjusting for relevant covariates including other lipid parameters, serum triglyceride level 150–199 mg/dL was not associated with death [hazard ratio (HR) 1.00, 95% confidence interval (95% CI) 0.92–1.10] relative to serum triglyceride |
| Databáze: | OpenAIRE |
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