Janus Face of Coronary Artery Disease and Chronic Kidney Disease
| Autor: | Dominic S. Raj, Ian R. Barrows |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Pathology
medicine.medical_specialty kidney Nephrology and Kidney medicine.medical_treatment Coronary Artery Disease 030204 cardiovascular system & hematology coronary disease Coronary artery disease 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans 030212 general & internal medicine Renal Insufficiency Chronic Cardiovascular mortality Original Research Accelerated atherosclerosis Kidney in Cardiovascular Disease business.industry Diabetes Type 2 medicine.disease humanities 3. Good health Heart failure diabetes mellitus Cardiology Kidney Failure Chronic Hemodialysis Cardiology and Cardiovascular Medicine business Kidney disease |
| Zdroj: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| ISSN: | 2047-9980 |
| Popis: | Background Although clear evidence shows that chronic kidney disease is a predictor of cardiovascular events, death, and accelerated coronary artery disease (CAD) progression, it remains unknown whether CAD is a predictor of progression of chronic kidney disease to end‐stage renal disease. We sought to assess whether CAD adds prognostic information to established predictors of progression to dialysis in patients with chronic kidney disease, diabetes, and anemia. Methods and Results Using the previously described Trial to Reduce Cardiovascular Events With Aranesp Therapy (TREAT) population, we compared baseline characteristics of patients with and without CAD. Cox proportional hazards models were used to assess the association between CAD and the outcomes of end‐stage renal disease and the composite of death or end‐stage renal disease. Of the 4038 patients, 1791 had a history of known CAD. These patients were older (mean age 70 versus 65 years, P |
| Databáze: | OpenAIRE |
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