The thrombin generation assay distinguishes inhibitor from non-inhibitor patients with severe haemophilia A

Autor:	Maria Elisa Mancuso, Armando Tripodi, Erica Scalambrino, Lidia Padovan, Elena Santagostino, Marigrazia Clerici, Maria Rosaria Fasulo, Veena Chantarangkul, Flora Peyvandi
Rok vydání:	2016
Předmět:	Adult Male congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty Genotype Haemophilia A 030204 cardiovascular system & hematology Hemophilia A medicine.disease_cause Severity of Illness Index Thrombin generation 03 medical and health sciences 0302 clinical medicine Thrombin Internal medicine medicine Humans Genetics (clinical) Blood coagulation test Mutation Factor VIII business.industry Hematology General Medicine Middle Aged medicine.disease Antibodies Neutralizing Titer Endocrinology Immunology Severe haemophilia A Blood Coagulation Tests business 030215 immunology medicine.drug
Zdroj:	Haemophilia. 22:e286-e291
ISSN:	1351-8216
Popis:	Introduction Patients with haemophilia A (HA) have impaired thrombin generation (TG) capacity and TG assay (TGA) values are linearly related to plasma factor VIII (FVIII) levels. Aim This study carried out in patients with unmeasurable FVIII (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82326c2672aa966f03558878a9c5c0ed https://doi.org/10.1111/hae.12927 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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