Genetic Polymorphism of Glycine-Rich Beta-Glycoprotein in the Italian Population

Autor: F Peyretti, R. Pflugshaupt, René Bütler, R. Scherz
Rok vydání: 1982
Předmět:
Zdroj: Human Heredity. 32:11-14
ISSN: 1423-0062
0001-5652
DOI: 10.1159/000153253
Popis: Genetic polymorphism of glycine-rich beta-glycoprotein (GBG) was studied in populations from northern and southern Italy, respectively. Gene frequencies were as follows: northern Italy (n = 431): GbS = 0.7675, GbF = 0.2049, GbS 0.7 = 0.0127, GbF1 = 0.0139; southern Italy (n = 161): GbS = 0.7050, GbF = 0.2360, GbS 0.7 = 0.0373, GbF1 = 0.0217. Comparison of these two populations with the Swiss population revealed a significant drift in gene frequencies from north to south. A new GBG phenotype, supposedly heterozygous, with a slow migrating F band and a regular S band in agarose electrophoresis was observed.
Databáze: OpenAIRE