Ultrasound Shear-Wave Elastography of the Tongue in Adults with Obstructive Sleep Apnea
| Autor: | Ya Hui Wang, Chun Hsiang Chang, Chih-Chung Huang, Jeng-Wen Chen, Fang Ju Chou |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Acoustics and Ultrasonics Biophysics Polysomnography Young Adult 03 medical and health sciences 0302 clinical medicine Tongue Internal medicine medicine Humans Radiology Nuclear Medicine and imaging Prospective Studies Aged Sleep Apnea Obstructive Radiological and Ultrasound Technology medicine.diagnostic_test Receiver operating characteristic business.industry Ultrasound Middle Aged medicine.disease respiratory tract diseases Obstructive sleep apnea medicine.anatomical_structure 030228 respiratory system Case-Control Studies Dilator Breathing Cardiology Elasticity Imaging Techniques Female business Airway 030217 neurology & neurosurgery |
| Zdroj: | Ultrasound in Medicine & Biology. 46:1658-1669 |
| ISSN: | 0301-5629 |
| Popis: | Obstructive sleep apnea (OSA) is a chronic breathing disorder characterized by intermittent sleep state-dependent upper airway (UA) collapse. The tongue comprises the primary UA dilator muscle and plays an essential role in the pathogenesis of OSA. We examined whether tongue stiffness measurement using ultrasound (US) shear wave elastography (SWE) is useful for predicting the existence of OSA. Forty-six participants (20 healthy controls and 26 patients with OSA) underwent transcutaneous submental SWE using a US system. Quantification with a shear modulus of 0-200 kPa was recorded during normal breathing and Muller's maneuver (MM). Polysomnography was used as the reference standard. Mid-sagittal tongue stiffness was significantly higher in awake patients with OSA than in controls during normal breathing and the MM (p < 0.0001). The posterior third of the tongue in patients with OSA had the highest value of shear modulus during the MM (p < 0.001). With cut-offs of 27.6 and 35.2 kPa for the whole tongue and posterior third during the MM, respectively, the sensitivity obtained was 69.2% and 76.9%, and the specificity was 85% and 95%, respectively, for detecting OSA. The corresponding areas under the receiver operating characteristic curve were 0.82 and 0.88, respectively. US SWE may have the potential for non-invasive tongue stiffness measurement in OSA. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|