Prostatic Arterial Embolization to Treat Benign Prostatic Hyperplasia
| Autor: | J. Mendes, Marisa Duarte, Antonio Gouveia Oliveira, Tiago Bilhim, João Pisco, L. Pinheiro |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Male
Time Factors medicine.medical_treatment Biopsy Prostatic Hyperplasia Pilot Projects Álcool de Polivinil Prostate Ischemia Erecção do Pénis Embolization Prospective Studies Ultrasonography Aged 80 and over Arterial Embolization Penile Erection Arteries Organ Size Middle Aged Embolization Therapeutic Magnetic Resonance Imaging Prostatic artery embolization Recuperação da Função Fisiológica Prostate-specific antigen Biópsia Estudos de Viabilidade Factores de Tempo medicine.anatomical_structure Treatment Outcome Embolização Terapêutica International Prostate Symptom Score Hiperplasia Prostática Cardiology and Cardiovascular Medicine medicine.medical_specialty Estudos Prospectivos Urinary system Ultrassonografia Urinary Bladder Bexiga Efeitos Adversos Tamanho do Órgão Lower urinary tract symptoms Resultado de Tratamento medicine Humans Radiology Nuclear Medicine and imaging Ressonância Magnética Urodinâmica Aged Portugal business.industry Artérias Recovery of Function Prostate-Specific Antigen medicine.disease Próstata Antigénio Prostático Específico Surgery Isquemia Projectos Piloto Urodynamics Polyvinyl Alcohol Quality of Life Feasibility Studies business Qualidade de Vida |
| Zdroj: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação instacron:RCAAP |
| Popis: | Purpose To evaluate whether prostatic arterial embolization (PAE) might be a feasible procedure to treat lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH). Materials and Methods Fifteen patients (age range, 62–82 years; mean age, 74.1 y) with symptomatic BPH after failure of medical treatment were selected for PAE with nonspherical 200-μm polyvinyl alcohol particles. The procedure was performed by a single femoral approach. Technical success was considered when selective prostatic arterial catheterization and embolization was achieved on at least one pelvic side. Results PAE was technically successful in 14 of the 15 patients (93.3%). There was a mean follow-up of 7.9 months (range, 3–12 months). International Prostate Symptom Score decreased a mean of 6.5 points ( P = .005), quality of life improved 1.14 points ( P = .065), International Index of Erectile Function increased 1.7 points ( P = .063), and peak urinary flow increased 3.85 mL/sec ( P = .015). There was a mean prostate-specific antigen reduction of 2.27 ng/mL ( P = .072) and a mean prostate volume decrease of 26.5 mL ( P = .0001) by ultrasound and 28.9 mL ( P = .008) by magnetic resonance imaging. There was one major complication (a 1.5-cm 2 ischemic area of the bladder wall) and four clinical failures (28.6%). Conclusions In this small group of patients, PAE was a feasible procedure, with preliminary results and short-term follow-up suggesting good symptom control without sexual dysfunction in suitable candidates, associated with a reduction in prostate volume. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|