Association between cardiac troponin I and mortality in patients with COVID-19
| Autor: | Giuseppe Moriello, Emanuela Morenghi, Francesco Paolo Leone, Michela Salvatici, Barbara Barbieri, Federica Maura, Sara Maria Giulia Cioffi, Maria Teresa Sandri |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty 2019-20 coronavirus outbreak Cardiac troponin Coronavirus disease 2019 (COVID-19) Health Toxicology and Mutagenesis Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Clinical Biochemistry 030204 cardiovascular system & hematology Biochemistry Risk Assessment 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine cardiac troponin medicine Humans In patient Pathological Pandemics serially measurements of hs-TnI Aged Retrospective Studies Aged 80 and over Heart Failure business.industry SARS-CoV-2 Troponin I COVID-19 Middle Aged medicine.disease musculoskeletal system mortality Hospitalization Pneumonia ROC Curve 030220 oncology & carcinogenesis Original Article Female business Biomarkers Research Article |
| Zdroj: | Biomarkers article-version (VoR) Version of Record |
| ISSN: | 1366-5804 1354-750X |
| Popis: | Background Severe pneumonia is pathological manifestation of Coronavirus Disease 2019 (COVID-19), however complications have been reported in COVID-19 patients with a worst prognosis. Aim of this study was to evaluate the role of high sensitivity cardiac troponin I (hs-TnI) in patients with SARS-CoV-2 infection. Methods we retrospectively analysed hs-TnI values measured in 523 patients (median age 64 years, 68% men) admitted to a university hospital in Milan, Italy, and diagnosed COVID-19. Results A significant difference in hs-TnI concentrations was found between deceased patients (98 patients) vs discharged (425 patients) [36.05 ng/L IQR 16.5–94.9 vs 6.3 ng/L IQR 2.6–13.9, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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