A comparison of ThinPrep Imager-assisted with manual screening, and its place in the New Zealand cervical cancer screening program
| Autor: | Elizabeth Pringle, Mee Ling Yeong, Joanna Stewart, Erin Retter |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Diagnostic Imaging
medicine.medical_specialty Concordance Uterine Cervical Neoplasms Abnormal cell Cervix Uteri Cervical cancer screening Sensitivity and Specificity Pathology and Forensic Medicine medicine Humans Diagnosis Computer-Assisted Diagnostic Errors Early Detection of Cancer Vaginal Smears Gynecology Pathology Clinical Cervical screening Obstetrics business.industry Initial screen Clinical method Female Clinical Competence Clinical competence Detection rate business New Zealand |
| Zdroj: | Pathology. 45:474-477 |
| ISSN: | 0031-3025 |
| DOI: | 10.1097/pat.0b013e3283631d63 |
| Popis: | Summary Aims Overseas studies have shown equivalent sensitivity and specificity between computer-assisted screening and manual screening, with increased screener productivity. This study was undertaken to test these in a New Zealand laboratory setting. Methods A total of 9232 slides were read manually alone, and following ThinPrep Imager-assisted screening, and the results compared. Two senior screeners and a cytopathologist reviewed the slides with discordant results. Results: The detection rate for abnormalities was 7.30% for Imager-assisted screening and 7.83% for manual screening. The concordance in diagnosis of abnormalities ranged from 72.7% to 100% with the lowest concordance for high-grade abnormalities diagnosed by Imager-assisted screening. The rate of unsatisfactory smears with Imager-assisted screening is half that of manual screening. There was a screener productivity increase of 140%. In all but one case, abnormal cells were identified by the Imager but screeners varied in their interpretations. Conclusions Overall, Imager-assisted screening was as sensitive as manual screening, and more sensitive for high- grade lesions, with a halving of the rate of unsatisfactory smears. In the setting of the New Zealand cervical screening program, the initial screen by the Imager removes the need for a second, rapid rescreen required by the program for manual screening. |
| Databáze: | OpenAIRE |
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