Assessment of a Sixteen-Week Training Program on Strength, Pain, and Function in Rheumatoid Arthritis Patients
| Autor: | Jeffrey R. Lisse, Donald Gates, David E. Yocum, Timothy G. Lohman, Scott B. Going, Ellen Cussler, Terri Guido, H G. Flint-Wagner |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male musculoskeletal diseases medicine.medical_specialty Strength training Arthritis Pilot Projects law.invention Arthritis Rheumatoid Disability Evaluation Rheumatology Randomized controlled trial law Humans Medicine Longitudinal Studies Muscle Strength Exercise physiology Exercise Aged business.industry Antibodies Monoclonal Resistance Training Middle Aged medicine.disease Arthralgia Combined Modality Therapy Health Surveys Infliximab Treatment Outcome Antirheumatic Agents Rheumatoid arthritis Muscle strength Physical therapy Female business Training program medicine.drug |
| Zdroj: | JCR: Journal of Clinical Rheumatology. 15:165-171 |
| ISSN: | 1076-1608 |
| DOI: | 10.1097/rhu.0b013e318190f95f |
| Popis: | To assess the effects of a 16-week progressive, individualized, high-intensity strength training program on muscle strength, pain, and function in patients with rheumatoid arthritis (RA).Twenty-four RA patients (men, n = 5; women, n = 19) receiving infliximab participated in a randomized controlled trial. The strength training (ST) group (n = 16) participated in a supervised program 3 times per week, and the control (C) group (n = 8) continued with standard of care as overseen by their rheumatologist. Assessments were completed at baseline and at weeks 8 and 16. Strength was measured by 3 repetition maximum (3RM), isometric hand dynamometer, and isokinetic dynamometer. A 100-mm visual analogue scale was used to assess pain. Functional performance was derived from a timed 50-foot walk and the Health Assessment Questionnaire Disability Index.The mean percent increase in strength (3RM) for the ST group from baseline to week 16 was 46.1% +/- 31.6% (P0.01) (mean of all three 3RM exercises: hammer curl, leg press, and incline dumbbell press), with mean gains in strength up to 4 times that of baseline values reported in all strength training exercises (upper and lower body) performed during exercise sessions. On average, right-hand grip strength increased by 2.9 +/- 4.0 kg in the ST group, in comparison with a loss of 1.2 +/- 3.0 kg in the C group over 16 weeks. The ST group had a 53% reduction in pain, in comparison with almost no change in the C group. The ST group had a significant improvement in 50-foot walk time, with a mean reduction of -1.2 +/- 1.6 seconds, in comparison with the C group (mean increase of 0.8 +/- 1.0 seconds; P = 0.01) over the 16 weeks. There was a clinically important difference (predefined as mean change +/-0.25) in the Health Assessment Questionnaire Disability Index in the ST group (-0.4 +/- 0.4) but not in the C group (-0.1 +/- 0.4).High-intensity strength training in RA patients with varying levels of disease activity and joint damage had a large, significant effect on strength, and led to improvements in pain and function, with additive patient benefits beyond the effect of their infliximab use. |
| Databáze: | OpenAIRE |
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