| Autor: |
Choi, Horace C. W., Leung, Kathy, Chan, Karen K. L., Bai, Yuan, Jit, Mark, Wu, Joseph T. |
| Rok vydání: |
2023 |
| DOI: |
10.6084/m9.figshare.22606169 |
| Popis: |
Additional file 1: Supplementary Information. This file provides additional information on model description, parameterization and calibration, settings on cervical screening and HPV vaccination used in the study, extra data for performing the cost-effectiveness analysis, and the supplementary results on sensitivity analyses. Table S1. The distribution of individuals by the level of sexual activity and age group. Table S2. Age distribution and mortality rate in Hong Kong. Table S3. Posterior distributions of inferred parameters. Table S4. Test performance parameters of cytology and HPV test. Table S5. Cost-effectiveness of guidelines-based screening strategies for unvaccinated cohorts. Table S6. ICERs of the most cost-effective screening strategy by vaccine uptake and duration of vaccine protection for unvaccinated cohorts. Table S7. Cost-effectiveness of screening strategies by annual discount rates for unvaccinated cohorts. Table S8. Sensitivity analysis on the estimated costs and health outcomes for unvaccinated cohorts by screen uptake. Table S9. Cost-effectiveness of guidelines-based screening strategies for vaccinated cohorts. Table S10. ICERs of the most cost-effective screening strategy by vaccine uptake and duration of vaccine protection for vaccinated cohorts. Table S11. Cost-effectiveness of screening strategies by annual discount rates for vaccinated cohorts. Table S12. Cost-effectiveness of screening strategies for vaccinated cohorts, with the assumption of faster HPV clearance rate and waning rate of natural immunity in males. Table S13. Sensitivity analysis of the estimated cost and health outcomes of screening strategies for vaccinated cohorts by screening uptake. Table S14. One-way sensitivity analysis on the cost-effectiveness of variants of strategy HPV + Genotyping for vaccinated cohorts. Table S15. Cost-effectiveness of variants of strategy HPV + Genotyping for vaccinated cohorts. Fig. S1. Schematic of the natural history model for high-risk HPV infection and cervical cancer. Fig. S2. Comparison of empirical data and the fitted model. Fig. S3. Trace plots and the posterior distributions of fitted parameters. Fig. S4. Schematic of evaluated cervical screening algorithms. Fig. S5. One-way sensitivity analysis of ICER for unvaccinated cohorts. Fig. S6. One-way sensitivity analysis of ICER for vaccinated cohorts. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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