Family nurture intervention in preterm infants increases early development of cortical activity and independence of regional power trajectories

Autor: Robert J. Ludwig, Philip G. Grieve, Raymond I. Stark, Michael M. Myers, Joseph L. Barone, Martha G. Welch, Joseph R. Isler
Rok vydání: 2017
Předmět:
Zdroj: Acta Paediatrica. 106:1952-1960
ISSN: 0803-5253
Popis: Aim Premature delivery and maternal separation during hospitalization increase infant neurodevelopmental risk. Previously, a randomized controlled trial of Family Nurture Intervention (FNI) in the neonatal intensive care unit demonstrated improvement across multiple mother and infant domains including increased electroencephalographic (EEG) power in the frontal polar region at term age. New aims were to quantify developmental changes in EEG power in all brain regions and frequencies and correlate developmental changes in EEG power among regions. Methods EEG (128 electrodes) was obtained at 34-44 weeks postmenstrual age from preterm infants born 26-34 weeks. 44 infants were treated with Standard Care and 53 with FNI. EEG power was computed in 10 frequency bands (1 to 48 Hz) in 10 brain regions and in active and quiet sleep. Results Percent change/week in EEG power was increased in FNI in 132/200 tests (p
Databáze: OpenAIRE