Prevalence, geographical distribution and factors associated with pentavalent vaccine zero dose status among children in Sindh, Pakistan: analysis of data from the 2017 and 2018 birth cohorts enrolled in the provincial electronic immunisation registry

Autor: Mariam Mehmood, Hamidreza Setayesh, Danya Arif Siddiqi, Muhammad Siddique, Sundus Iftikhar, Riswana Soundardjee, Vijay Kumar Dharma, Ahsanullah Khan Bhurgri, E M Stuckey, Muhammad Akram Sultan, Subhash Chandir
Rok vydání: 2022
Předmět:
Zdroj: BMJ Open. 12:e058985
ISSN: 2044-6055
DOI: 10.1136/bmjopen-2021-058985
Popis: ObjectivesTo estimate the prevalence of zero dose children (who have not received any dose of pentavalent (diphtheria, tetanus, pertussis, Haemophilus influenzae type B and hepatitis B) vaccine by their first birthday) among those who interacted with the immunisation system in Sindh, Pakistan along with their sociodemographic characteristics and risk factors.Design and participantsWe conducted a descriptive analysis of child-level longitudinal immunisation records of 1 467 975 0–23 months children from the Sindh’s Zindagi Mehfooz (Safe Life) Electronic Immunisation Registry (ZM-EIR), for the birth cohorts of 2017 and 2018.SettingSindh province, Pakistan which has a population of 47.9 million people and an annual birth cohort of 1.7 million.Primary and secondary outcome measuresThe primary outcome measure was zero dose status among enrolled children. Logistic regression was performed to identify the risk factors associated with the zero dose status.ResultsOut of 1 467 975 children enrolled in the ZM-EIR in Sindh, 10.6% (154 881/1 467 975) were zero dose. There were sharp inequities across the 27 districts. Zero dose children had a lower proportion of hospital births (28.5% vs 34.0%; difference 5.5 percentage points (pp) (95% CI 5.26 to 5.74); pConclusionsDespite interacting with the immunisation system, 1 out of 10 children enrolled in the ZM-EIR in Sindh were zero dose. It is crucial to monitor the prevalence of zero dose children and investigate their characteristics and risk factors to effectively reach and follow-up with them.
Databáze: OpenAIRE