Multi-center study on overall clinical complexity of patients with prolonged disorders of consciousness of different etiologies
| Autor: | G P Salvi, A R Diana, Valeria Pingue, Michelangelo Bartolo, Anna Estraneo, S Premoselli, F De Bellis, Rita Formisano, Domenico Intiso, R Antenucci, M Gambarin, Federico Scarponi, P Bongioanni, C Perin, A De Tanti, Orsola Masotta, Annamaria Romoli, Francesca Pistoia, S Gentile, Elena Rossato, Silvia Marino, Antonino Sant'Angelo, E Casanova, Lucia Francesca Lucca, M Bertoni |
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| Přispěvatelé: | Estraneo, A, Masotta, O, Bartolo, M, Pistoia, F, Perin, C, Marino, S, Lucca, L, Pingue, V, Casanova, E, Romoli, A, Gentile, S, Formisano, R, Salvi, G, Scarponi, F, De Tanti, A, Bongioanni, P, Rossato, E, Santangelo, A, Diana, A, Gambarin, M, Intiso, D, Antenucci, R, Premoselli, S, Bertoni, M, De Bellis, F |
| Rok vydání: | 2020 |
| Předmět: |
030506 rehabilitation
medicine.medical_specialty Consciousness medicine.medical_treatment Neuroscience (miscellaneous) 03 medical and health sciences 0302 clinical medicine Internal medicine Developmental and Educational Psychology Medicine Humans clinical complexity Disorders of consciousne Neurorehabilitation Persistent vegetative state Coma Disorders of consciousness neurorehabilitation Rehabilitation business.industry Persistent Vegetative State Minimally conscious state medical complications outcome medical complication Disability Rating Scale medicine.disease Cross-Sectional Studies Brain Injuries Etiology Consciousness Disorders Wakefulness Neurology (clinical) medicine.symptom 0305 other medical science business 030217 neurology & neurosurgery |
| Zdroj: | Brain injury. 35(1) |
| ISSN: | 1362-301X |
| Popis: | Aim: to assess overall clinical complexity of patients with acquired disorders of consciousness (DoC) in vegetative state/unresponsive wakefulness syndrome (VS/UWS) vs. minimally conscious state- MCS) and in different etiologies. Design: Multi-center cross-sectional observational study. Setting: 23 intensive neurorehabilitation units. Subjects: 264 patients with DoC in the post-acute phase: VS/UWS = 141, and MCS = 123 due to vascular (n = 125), traumatic (n = 83) or anoxic (n = 56) brain injury. Main Measures: Coma Recovery Scale-Revised, and Disability Rating Scale (DRS); presence of medical devices (e.g., for eating or breathing); occurrence and severity of medical complications. Results: patients in DoC, and particularly those in VS/UWS, showed severe overall clinical complexity. Anoxic patients had higher overall clinical complexity, lower level of responsiveness/consciousness, higher functional disability, and higher needs of medical devices. Vascular patients had worse premorbid clinical comorbidities. The two etiologies showed a comparable rate of MC, higher than that observed in traumatic etiology. Conclusion: overall clinical complexity is significantly higher in VS/UWS than in MCS, and in non-traumatic vs. traumatic etiology. These findings could explain the worse clinical evolution reported in anoxic and vascular etiologies and in VS/UWS patients and contribute to plan patient-tailored care and rehabilitation programmes. |
| Databáze: | OpenAIRE |
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