Reduced Context Effects on Retrieval in First-Episode Schizophrenia
| Autor: | Lieuwe de Haan, Lucia M. Talamini, Don H. Linszen, Dorien H. Nieman, Martijn Meeter |
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| Přispěvatelé: | Cognitive Psychology, Faculteit der Geneeskunde, Brein en Cognitie (Psychologie, FMG), Amsterdam Neuroscience, Adult Psychiatry |
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Adult
Male Adolescent Mental Health/Neuropsychiatric Disorders Schizophrenia (object-oriented programming) lcsh:Medicine Context (language use) Biology First episode schizophrenia behavioral disciplines and activities 03 medical and health sciences Young Adult 0302 clinical medicine mental disorders Humans Young adult lcsh:Science Episodic memory Neuroscience/Cognitive Neuroscience Mental Health/Schizophrenia and Other Psychoses Memory Disorders Multidisciplinary Neuroscience/Behavioral Neuroscience Recall Context effect lcsh:R Mental Health/Psychology 030227 psychiatry Neuroscience/Psychology Mental Health Memory Short-Term Case-Control Studies Word recognition Schizophrenia lcsh:Q Female Cues Cognition Disorders 030217 neurology & neurosurgery Cognitive psychology Research Article |
| Zdroj: | PLoS ONE PLoS ONE, 5. Public Library of Science PLoS ONE, Vol 5, Iss 4, p e10356 (2010) Talamini, L M, Haan, L, Nieman, D H, Linszen, D H & Meeter, M 2010, ' Reduced context effects on retrieval in first-episode schizophrenia ', PLoS ONE, vol. 5, pp. e10356 . https://doi.org/10.1371/journal.pone.0010356 PLoS ONE, 5(4):e10356. Public Library of Science PLoS ONE, 5(4). Public Library of Science |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0010356 |
| Popis: | Background: A recent modeling study by the authors predicted that contextual information is poorly integrated into episodic representations in schizophrenia, and that this is a main cause of the retrieval deficits seen in schizophrenia. & Methodology/Principal Findings: We have tested this prediction in patients with first-episode schizophrenia and matched controls. The benefit from contextual cues in retrieval was strongly reduced in patients. On the other hand, retrieval based on item cues was spared. & Conclusions/Significance: These results suggest that reduced integration of context information into episodic representations is a core deficit in schizophrenia and one of the main causes of episodic memory impairment. © 2010 Talamini. |
| Databáze: | OpenAIRE |
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