Antibodies against Chlamydia pneumoniae in stable angina and interleukin-6 levels
| Autor: | Vicente Herreros-Fernandez, Candelas Gonzalez-Castaneda, Marı́a-Luisa Arranz-Peña, Victor Gonzalez, José-Luis Pérez-Castrillón |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2003 |
| Předmět: |
Male
medicine.medical_specialty Cardiovascular Aparato - Enfermedades Heart disease Inflammation Fibrinogen Antibodies Angina Pectoris Coronary artery disease Angina Neumonia Internal medicine medicine Humans biology business.industry Interleukin-6 Acute-phase protein Antibody titer Chlamydophila pneumoniae medicine.disease Immunology biology.protein Cardiology Female medicine.symptom Antibody Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | UVaDOC. Repositorio Documental de la Universidad de Valladolid instname |
| DOI: | 10.1016/s0167-5273(02)00383-2 |
| Popis: | Producción Científica Inflammation is a key mechanism in atherogenesis and the rapid progression of coronary artery disease. Tissue lesion occasions the release of chemical mediators, cytokines, accompanied by an increase in the blood concentrations of acute phase reactants, such as fibrinogen, C-reactive protein, serum amyloid A protein, sialic acid and ceruloplasmin and a reduction of those of albumin. It has been observed that these proteins are higher in patients with is-chemic heart disease and, furthermore, who have a higher tendency to present adverse cardiovascular incidents [1]. On the other hand, the inflammation appears to be directly linked to the ‘vulnerability’ or ‘instability’ of the atheromatous plaques that pre-dispose to disruption and acute coronary incidents. The inflammatory mechanism, therefore, can repre-sent the final common connection channel of chronic infection between atherogenesis and the clinical manifestations of coronary artery disease [2]. |
| Databáze: | OpenAIRE |
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