Biomechanical CT-computed bone strength predicts the risk of subsequent vertebral fracture

Autor: Fei, Song, Yi, Wei, Wentian, Feng, Ruisen, Fu, Zuchang, Li, Xing, Gao, Xiaoguang, Cheng, Haisheng, Yang
Rok vydání: 2023
Předmět:
Zdroj: Bone. 166:116601
ISSN: 8756-3282
DOI: 10.1016/j.bone.2022.116601
Popis: Following primary fractures and percutaneous kyphoplasty (PKP), patients have a high risk of incurring a subsequent vertebral fracture (SVF). Given that SVF is a consequence of mechanical deterioration of the vertebra, we sought to examine whether vertebral strength derived from QCT-based finite element analysis (i.e., BCT) can predict the risk of SVF. Sixty-six patients who underwent PKP were categorized into two groups: control or non-SVF group (age: 70 ± 7 years; n = 40) and SVF group (age: 69 ± 8 years; n = 26). BCT was performed on L4 or L3 vertebrae to noninvasively measure vertebral strength. Vertebral strength was also estimated based upon the geometry and material properties of the vertebra. Additionally, trabecular volumetric bone mineral density (vBMD) and L1 Hounsfield unit (HU) were measured. t-Test, χ
Databáze: OpenAIRE