Effects of Use and Disuse on Nerve Endings, Neurosomes, and Fiber Types in Skeletal Muscle
| Autor: | Eben J. Carey, Eli Socoloff, Haushalter Eugene, Lynch John, Leo C. Massopust, Garofalo Frank, Tabat Denis |
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| Rok vydání: | 1947 |
| Předmět: |
Nerve Endings
Nervous system Chemistry Muscles medicine.medical_treatment Tenotomy Skeletal muscle Anatomy medicine.disease General Biochemistry Genetics and Molecular Biology Muscular Atrophy Gastrocnemius muscle medicine.anatomical_structure Atrophy medicine Humans Nervous System Physiological Phenomena Fiber Muscle Skeletal Free nerve ending Muscle contracture |
| Zdroj: | Experimental Biology and Medicine. 64:193-200 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-64-15744 |
| Popis: | SummaryThe limited experimental evidence presented in this paper tends to support the following statements:The normally used and innervated gastrocnemius muscle of the white rat is characterized histologically by dark, coarsely granular and light, finely granular and agranular muscle fibers. The nerve endings are usually retracted in the dark, coarsely granular fiber and expanded in the light, agranular fiber, as revealed by gold impregnation of teased whole muscle fibers. The atrophy of disuse following tenotomy of the gastrocnemius muscle with nerve supply intact, is accompanied, during the first month, by the progressive loss of the narrow and dark, coarsely granular muscle fiber, and by a depletion of its innervation. The dark, granular muscle fiber is determined by the reciprocal interaction of the normally intact and attached muscle fiber with its normally functioning innervation. During the process of atrophy of disuse after tenotomy, small and giant fusiform neurosomes are discharged from the alte... |
| Databáze: | OpenAIRE |
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