Substance use disorder and risk of suicidal ideation, suicide attempt and suicide death: a meta-analysis
Autor: | Tahereh Haghtalab, Jalal Poorolajal, Nahid Darvishi, Mehran Farhadi |
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Rok vydání: | 2016 |
Předmět: |
Adult
Male medicine.medical_specialty Adolescent Substance-Related Disorders Poison control Suicide Attempted Suicide prevention Suicidal Ideation 03 medical and health sciences Young Adult 0302 clinical medicine Sex Factors Risk Factors medicine Humans 030212 general & internal medicine Psychiatry Child Suicidal ideation Aged Aged 80 and over Suicide attempt business.industry Public Health Environmental and Occupational Health Age Factors General Medicine Odds ratio Middle Aged 030227 psychiatry Suicide Meta-analysis Relative risk Child Preschool Cohort Female medicine.symptom business |
Zdroj: | Journal of public health (Oxford, England). 38(3) |
ISSN: | 1741-3850 |
Popis: | BACKGROUND: This meta-analysis addressed the association between substance use disorder (SUD) and suicide outcomes based on current evidence. METHODS: We searched PubMed, Web of Science and Scopus until May 2015. We also searched the reference lists of included studies and Psycinfo website. We included observational (cohort, case-control, cross-sectional) studies addressing the association between SUD and suicide. Our outcomes of interest were suicide ideation, suicide attempt and suicide death. For each outcome, we calculated the odds ratio (OR) or risk ratio (RR) with 95% confidence intervals (CI) based on the random-effects model. RESULTS: We identified a total of 12 413 references and included 43 studies with 870 967 participants. There was a significant association between SUD and suicidal ideation: OR 2.04 (95% CI: 1.59, 2.50; I(2) = 88.8%, 16 studies); suicide attempt OR 2.49 (95% CI: 2.00, 2.98; I(2) = 94.3%, 24 studies) and suicide death OR 1.49 (95% CI: 0.97, 2.00; I(2) = 82.7%, 7 studies). CONCLUSIONS: Based on current evidence, there is a strong association between SUD and suicide outcomes. However, evidence based on long-term prospective cohort studies is limited and needs further investigation. Moreover, further evidence is required to assess and compare the association between suicide outcomes and different types of illicit drugs, dose-response relationship and the way they are used. Language: en |
Databáze: | OpenAIRE |
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