An antiviral meliacarpin from leaves of Melia azedarach L
| Autor: | Marta S. Maier, Celia E. Coto, Milena Meo, Guillermo Assad Ferek, Laura Edith Alche |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Limonins
biology Traditional medicine viruses Melia azedarach Ethyl acetate Herpesvirus 1 Human Microbial Sensitivity Tests biology.organism_classification Limonoid Virology Antiviral Agents General Biochemistry Genetics and Molecular Biology Vesicular stomatitis Indiana virus Plant Leaves Vesicular Stomatitis chemistry.chemical_compound chemistry Ic50 values medicine Monoterpenes Bioassay Biological Assay medicine.drug |
| Zdroj: | Zeitschrift fur Naturforschung. C, Journal of biosciences. 58(3-4) |
| ISSN: | 0939-5075 |
| Popis: | Bioassay guided purification of the ethyl acetate extract of leaves of Melia azedarach led to the isolation of the limonoid 1-cinnamoyl-3,11-dihydroxymeliacarpin, which showed IC50 values of 6 μᴍ and 20 μᴍ for vesicular stomatitis (VSV) and herpes simplex (HSV-1) viruses, respectively. Its structure was established by spectroscopic methods. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|